首页|True hyponatremia in the setting of pegasparagase-induced hypertriglyceridemia: A case report

True hyponatremia in the setting of pegasparagase-induced hypertriglyceridemia: A case report

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? 2022Pegasparagase (PEG-Asparaginase) induced hypertriglyceridemia is rare in the treatment of lymphoblastic lymphoma in children. We present a case of PEG-asparaginase induced hypertriglyceridemia that was incidentally identified and suspicion of its interference with sodium measurement in the clinical laboratory. The use of a direct ion selective method clarified the presence of true hyponatremia. The patient was treated with an oral Fenofibrate therapy which resolved the hypertriglyceridemia. This case highlights that PEG-asparaginanse and Olazanpine can induce hypertriglyceridemia in acute lymphoblastic leukemia and it may be useful to obtain baseline triglyceride measurements for these patients.

AsparaginaseHypertriglyceridemiaHyponatremiaPegasparagase

Olayinka L.、Poventud-Fuentes I.、Rahman Ansari S.、Garnett E.、Devaraj S.

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Department of Pathology and Immunology Baylor College of Medicine

2022

Clinica chimica acta

Clinica chimica acta

ISTP
ISSN:0009-8981
年,卷(期):2022.531
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