首页|Early life adversity blunts responses to pioglitazone in depressed, overweight adults
Early life adversity blunts responses to pioglitazone in depressed, overweight adults
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NSTL
Elsevier
Purpose: Early life adversity is associated with both metabolic impairment and depression in adulthood, as well as with poorer responses to antidepressant medications. It is not yet known whether individual differences in sensitivity to antidiabetic medications could also be related to early life adversity. We examined whether a history of early life adversity affected the observed changes in metabolic function and depressive symptoms in a randomized trial of pioglitazone for augmentation of standard treatments for depression.
NSTL
Elsevier
