首页|ONE STRAIN-MANY COMPOUNDS METHOD FOR PRODUCTION OF DIVERSE METABOLIC PROFILES USING Chaetomium sp.FROM Astragalus membranaceus
ONE STRAIN-MANY COMPOUNDS METHOD FOR PRODUCTION OF DIVERSE METABOLIC PROFILES USING Chaetomium sp.FROM Astragalus membranaceus
扫码查看
点击上方二维码区域，可以放大扫码查看
原文链接
NSTL
Previously,we found that the endophytic fungus AR-17-7 from the root of Astragalus membranaceus(Fisch.)Bunge associated with potato dextrose agar(PDA)media can produce structurally diverse chaetoglobosins.This encouraged further study on the use of the endophytic fungus AR-17-7 for the production of diverse metabolic profiles by the OSMAC technique.The OSMAC(one strain of many compounds)strategy,developed by Zeeck in the early 2000s,has been demonstrated to be a simple and effective method(1).In this strategy,the silent gene sequence was activated by changing culture conditions,including media composition,medium phase,and temperature(2).The OSMAC approach has been successfully applied to produce new secondary metabolites from single microbial strains during the last 10 years [3].
Hongchi Zhang、Rui Liu、Yang Yang
展开 >
College of Life Science,Shanxi Datong University,037009,Datong Shanxi,R R.China
NSTL
