首页|A FeS(2)NPs-Luminol-MnO(2)NSs system based on chemiluminescence resonance energy transfer platform for sensing glutathione
A FeS(2)NPs-Luminol-MnO(2)NSs system based on chemiluminescence resonance energy transfer platform for sensing glutathione
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NSTL
Elsevier
In this work, ferrous disulfide nanoparticles (FeS(2)NPs) with oxidase properties were synthesized, and a FeS(2)NPs-Luminol-MnO2 nanosheets (MnO(2)NSs) chemiluminescence resonance energy transfer (CRET) system was successfully established. Because of reaction with MnO(2)NSs, glutathione (GSH) can inhibit CRET between Luminol and MnO2NSs and recover the luminescence intensity of FeS(2)NPs-Luminol. Consequently, we developed a GSH sensor based on this chemiluminescence resonance energy transfer (CRET) system. Under optimal conditions, the FeS(2)NPs-Luminol-MnO(2)NSs sensing system showed very sensitive response to GSH in the range of 1 mu M-500 mu M. The limit of detection of GSH reached as low as 0.15 mu M. Finally, the sensor was successfully used for the detection of GSH in serum.
Ferrous disulfide nanoparticles (FeS(2)NPs)LuminolChemiluminescence resonance energy transfer (CRET)MnO2 nanosheets (MnO(2)NSs)Glutathione (GSH)ZNS QUANTUM DOTSFLUORESCENT SENSORMNO2 NANOSHEETSLUMINOLPYRITEPROBEADSORPTIONGLUCOSESURFACE