首页|Understanding and Harnessing Epithelial-Mesenchymal Interactions in the Development of Palmoplantar Identity

Understanding and Harnessing Epithelial-Mesenchymal Interactions in the Development of Palmoplantar Identity

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Palmoplantar skin has several unique characteristics such as increased thickness, high resilience, hypopigmentation, and lack of hair follicles. The establishment of palmoplantar identity occurs through keratinocyte-fibroblast interactions, with keratin 9 expression and Wnt signaling playing key roles. Understanding how palmoplantar features develop may help efforts to reproduce them at both palmoplantar and nonpalmoplantar body sites.

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Tsai, Jerry、Rostom, Mary、Garza, Luis A.

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Dept Dermatol,Johns Hopkins Sch Med

2022

The Journal of investigative dermatology.

The Journal of investigative dermatology.

ISSN:0022-202X
年,卷(期):2022.142(2)
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