首页|Understanding and Harnessing Epithelial-Mesenchymal Interactions in the Development of Palmoplantar Identity
Understanding and Harnessing Epithelial-Mesenchymal Interactions in the Development of Palmoplantar Identity
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NSTL
Elsevier
Palmoplantar skin has several unique characteristics such as increased thickness, high resilience, hypopigmentation, and lack of hair follicles. The establishment of palmoplantar identity occurs through keratinocyte-fibroblast interactions, with keratin 9 expression and Wnt signaling playing key roles. Understanding how palmoplantar features develop may help efforts to reproduce them at both palmoplantar and nonpalmoplantar body sites.