首页|Six new dammarane-type triterpene saponins from the processed leaves of Panax notoginseng
Six new dammarane-type triterpene saponins from the processed leaves of Panax notoginseng
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NSTL
Elsevier
? 2022 Phytochemical Society of EuropeSix new dammarane-type triterpenoid saponins, notoginsenosides SFt5–SFt10 (1–6) were isolated from the processed leaves of Panax notoginseng (Burk.) F.H.Chen (Araliaceae), together with eight known notoginsenosides (7–14), fourteen known ginsenosides (15?28), two known vinaginsenosides (29?30), and one known gypenoside (31). Their structures were established by detailed spectroscopic analysis (NMR, UV, IR, HRESI-MS) and acidic hydrolysis. Four compounds notoginsenoside SFt1 (7), ginsenosides Rg5 (17), C-Mc (23) and 20(R)–Rg3 (25) have significant protective effects against L-glutamate-induced SH–SY5Y nerve injury (10 μM).