首页|Schmorl's nodes could be associated with intervertebral disc degeneration at upper lumbar levels and end-plate disease at lower lumbar level in patients with low back pain
Schmorl's nodes could be associated with intervertebral disc degeneration at upper lumbar levels and end-plate disease at lower lumbar level in patients with low back pain
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NSTL
Elsevier
? 2022 Elsevier LtdSchmorl's nodes (SNs) have increasingly been recognized on vertebral end-plates using advanced imaging techniques. Even though vertebral end-plates are the closest structures to discs, their pathologies are underestimated in the etiology of low back pain (LBP). We aimed to detect the prevalence of SNs and other end-plate defects in subjects with/without LBP and to understand whether SNs were associated with LBP and spinal degeneration. Subjects were evaluated in terms of end-plate defects, intervertebral disc degeneration (IVDD), and vertebral end-plate changes (Modic changes) at all lumbar levels on lumbar spine magnetic resonance imagings (MRI). Control subjects were compared to patients with LBP. Higher Pfirrmann scores (OR: 2.696) and higher SN scores (OR: 8.076) were significantly associated with Modic changes at L4-L5 disc level. Patients with higher SN scores at L1-L2 or L2-L3 levels had approximately 7-fold increased risk of severe IVDD at the corresponding levels. The most significant factor associated with presence of SNs was body weight of the patients (OR: 1.417). The most significant factor associated with intensity of LBP was severe IVDD at L5-S1 level (OR: 3.670). Having higher total SN score had an OR of 1.230 (95% CI: 1.003–1.509; p = 0.047) for predicting LBP. Schmorl's nodes were seen in 33.1% of patients and 11.5% of asymptomatic subjects. Body weight was the most significant factor associated with SNs. The most significant factor associated with LBP was severe IVDD at L5-S1 level.
Disc degenerationEnd-plate changeLow back painSchmorl's nodes
Eksi M.S.、Turgut V.U.、Berikol G.、Ozmen B.B.、Huet S.E.、Dinc T.、Kucuksuleymanoglu D.、Orhun O.、Ozcan-Eksi E.E.
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Yeditepe University School of Medicine Neurosurgery Research Laboratory
Antalya Atatürk State Hospital Neurosurgery Clinic
Taksim Training and Research Hospital Neurosurgery Clinic
Ac?badem Mehmet Ali Ayd?nlar University School of Medicine
Bah?e?ehir University School of Medicine Department of Physical Medicine and Rehabilitation
NSTL
Elsevier
