首页|Simultaneous analysis of multiple pesticide residues in tobacco by magnetic carbon composite-based QuEChERS method and liquid chromatography coupled to quadrupole time-of-flight mass spectrometry

Simultaneous analysis of multiple pesticide residues in tobacco by magnetic carbon composite-based QuEChERS method and liquid chromatography coupled to quadrupole time-of-flight mass spectrometry

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  • NSTL
  • Elsevier
Magnetic carbon composite (Fe3O4@C) was synthesized and applied as a reversed-dispersive solid phase extraction sorbent for the simultaneous analysis of 40 pesticide residues in tobacco by ultrahigh performance liquid chromatography coupled to quadrupole time-of-fight mass spectrometry. Compared to the traditional QuEChERS method, the optimized Fe3O4@C simplified clean-up process and exhibited better clean-up capability than conventional sorbents. The pesticides were qualitatively identified by accurate mass of protonated molecules, fragment ions, isotopic peak clusters, and retention time, and quantitatively determined by matrix-matched external standard method. Good linearity of the proposed method was obtained with R value greater than 0.997 for all target pesticides at concentration levels of 2-200 mu g/L. The limit of detection ranged from 0.14 to 2.67 mu g/kg. The recoveries and relative standard deviations of all target pesticides at three spiked concentrations of 20, 50 and 200 mu g/kg were in the ranges of 80.8%-113.3% and 0.6%-16.3%, respectively. Compared with the reported methods for the analysis of multiple pesticide residues in tobacco, the proposed method has the advantages of simple to operate, high clean-up ability and less time-consuming in clean-up process. (C) 2022 Elsevier B.V. All rights reserved.

Pesticide multi-residue analysisTobaccoMagnetic carbon compositeClean-upLiquid chromatography coupled to quadrupole time-of-fight mass spectrometrySOLID-PHASE EXTRACTIONGAS-CHROMATOGRAPHYMULTIRESIDUE DETERMINATIONMULTIPESTICIDE RESIDUEDISPERSIVE EXTRACTIONASSISTED EXTRACTIONNANOTUBESCLEANUPFRUITSQUICK

Chen, Mantang、Chen, Li、Pan, Lining、Liu, Ruihong、Guo, Junwei、Fan, Meijuan、Wang, Xiaoyu、Liu, Huimin、Liu, Shaofeng

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CNTC

2022

10.1016/j.chroma.2022.462913

Journal of chromatography

Journal of chromatography

ISSN：0021-9673
年,卷(期)：2022.1668
  • 7
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