首页|A biodegradable in situ Zn-Mg 2 Ge composite for bone-implant applications

A biodegradable in situ Zn-Mg 2 Ge composite for bone-implant applications

扫码查看
原文链接
  • NSTL
  • Elsevier
Zinc (Zn)-based composites have received extensive attention as promising biodegradable materials due to their unique combination of moderate biodegradability, biocompatibility, and functionality. Nevertheless, the low mechanical strength of as-cast Zn-based composites impedes their practical clinical application. Here we reported the mechanical properties, corrosion behavior, wear properties, and cytotoxicity of in situ synthesized biodegradable Zn-xMg 2 Ge ( x = 1, 3, and 5 wt.%) composites for bone-implant applications. The mechanical properties of Zn-xMg 2 Ge composites were effectively improved by alloying and hot-rolling due to particle reinforcement of the Mg 2 Ge intermetallic phase and dynamic recrystallization. The hot-rolled (HR) Zn-3Mg 2 Ge composite exhibited the best mechanical properties, including a yield strength of 162.3 MPa, an ultimate tensile strength of 264.3 MPa, an elongation of 10.9%, and a Brinell hardness of 83.9 HB. With an increase in Mg 2 Ge content, the corrosion and degradation rates of the HR Zn-xMg 2 Ge composites gradually increased, while their wear rate decreased and then increased in Hanks' solution. The diluted extract (12.5% concentration) of the HR Zn-3Mg 2 Ge composite showed the highest cell viability compared to the other HR composites and their as-cast pure Zn counterparts. Overall, the HR Zn-3Mg 2 Ge composite can be considered a promising biodegradable Zn-based composite for bone-implant applications.

BiodegradabilityDegradation behaviorMechanical propertyMg 2 Ge intermetallic phaseWear resistanceZn-based compositesMECHANICAL-PROPERTIESMAGNESIUM ALLOYSMATRIX COMPOSITESZINC-DEFICIENCYORGANOGERMANIUM COMPOUNDSCORROSION-RESISTANCESTAINLESS-STEELPROTECTIVE ROLEBEHAVIORALUMINUM

Tong, Xian、Wang, Hongning、Zhu, Li、Han, Yue、Wang, Kun、Li, Yuncang、Ma, Jianfeng、Lin, Jixing、Wen, Cuie、Huang, Shengbin

展开 >

Sch & Hosp Stomatol,Wenzhou Med Univ

Coll Optoelect Mfg,Zhejiang Ind & Trade Vocat Coll

Sch Engn,RMIT Univ

2022

10.1016/j.actbio.2022.05.017

Acta biomaterialia

Acta biomaterialia

EISCI
ISSN：1742-7061
年,卷(期)：2022.146
  • 6
  • 127