Allyl sulfones construction via copper catalysis from alpha-methylstyrene derivatives and sulfonyl chlorides
Liu, Lixia 1Wang, Chengming1
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作者信息
1. Jinan Univ
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Abstract
Allyl sulfones are synthesized via Cu-catalyzed ligand-free regioselective sulfonylation reaction from easily obtained alpha-methylstyrene derivatives and sulfonyl chlorides. This redox-neutral protocol also features a low-cost metal catalyst, broad substrate scope, good functional group tolerance and could be smoothly amplified to a gram scale. The allylic sulfone products can be used in diverse radical coupling reactions. (C) 2021 Elsevier Ltd. All rights reserved.
NSTL
Elsevier