首页|Immunological underpinnings of Ascaris infection, reinfection and co-infection and their associated co-morbidities
Immunological underpinnings of Ascaris infection, reinfection and co-infection and their associated co-morbidities
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NSTL
Cambridge Univ Press
Abstract Human ascariasis is the most common and prevalent neglected tropical disease and is estimated that ~819 million people are infected around the globe, accounting for 0.861 million years of disability-adjusted life years in 2017. Even with the existence of highly effective drugs, the constant presence of infective parasite eggs in the environment contribute to a high reinfection rate after treatment. Due to its high prevalence and broad geographic distribution Ascaris infection is associated with a variety of co-morbidities and co-infections. Here, we provide data from both experimental models and humans studies that illustrate how complex is the interaction of Ascaris with the host immune system, especially, in the context of reinfections, co-infections and associated co-morbidities.
AllergyAscariscoinfectioncomorbiditiesfibrosis
Luisa,Magalh?es、Denise S.,Nogueira、Pedro H.,Gazzinelli-Guimar?es、Fabricio M. S.,Oliveira、Lucas,Kraemer、Ana Clara,Gazzinelli-Guimar?es、Flaviane,Vieira-Santos、Ricardo T.,Fujiwara、Lilian L.,Bueno
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Federal University of Minas Gerais
National Institute of Allergy and Infectious Diseases
NSTL
Cambridge Univ Press
