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Macmillan Magazines Ltd.
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Macmillan Magazines Ltd.

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0028-0836

Nature/Journal NatureSCI
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    Market moves

    Bec CrewTanner Maxwell
    S13-S17页
    查看更多>>摘要:More than 1 in 20 of all research moves within the United States for the period 2020-24 were from academia to companies, according to data from Sydney-based analytics company League of Scholars. Moves were calculated based on verified Google Scholar accounts affiliated with company e-mail domains, which means moves in countries where Google Scholar use is relatively low among corporate researchers, such as China, might be underrepresented. US companies lead as top destinations for academics moving to corporate research roles, based on 68,210 verified global cross-sector movements for 2020-24. Nearly 4% of these transitions were to Amazon and Google, with just over 2.5% specifically to Amazon.

    Why China's innovation model is thriving

    Jacob Dreyer
    S6-S7页
    查看更多>>摘要:An increasing number of Chinese com-panies are grabbing the headlines with new technologies rolled out at scale. The most prominent example in 2025 has been DeepSeek and its low-cost large language models, but others include electric-vehicle (EV) maker BYD - which this year launched its 'God's Eye' intelligent driving system as a standard feature on most of its models - and battery manufacturer CATL, which is planning a major expansion of 'swapping stations' in China that allowquick battery replacement in EVs. Underlying such roll-outs is a commitment to research and development and an increasing synergy between China's top universities and its private sector. In many ways, collaboration between academia and industry in China, especially when it comes to launching new compa-niesand products, issimilar to how things work in the West. It is increasingly structured around a high-risk, high-reward funding philosophy in which promising ideas originating in academia are given investment, even if the vast majority of them fail. But unlike well-established university-industry ecosystems such as Silicon Valley, where private investors typically dominate and accept the risk of most start-up businesses failing, in China, the state plays a pivotal role. National government departments, including the Ministry of Science and Technology (MOST), and local innovation funds are pouring billions of yuan into university-affiliated businesses, knowing most will not achieve commercial success. However, those that do can go on to redefine whole industries.

    GIVING PLASTICS A WHOLE LEASE OF LIFE

    S18-S19页
    查看更多>>摘要:Discarded plastics, which can persist in the environment for hundreds of years, threaten waterways, ecosystems and even human health. Yet solving the global plastics crisis through increased recycling is proving to be a major challenge. Only about 9% of plastic waste is effectively recycled worldwide due to a set of complex obstacles. Contaminants can damage recycling equipment and degrade the quality of recovered materials. Sorting the different types of plastics is labour-intensive and technically demanding. And even when plastics are successfully recycled, repeated processing often reduces their strength, colour and flexibility, limiting the number of times they can be reused. "The long-chain molecules in polymers, which form plastics, are like strands of noodles," explains materials scientist, Jianjun Li. "Just as boiling noodles repeatedly causes them to become mushy and break apart, repeatedly heating polymers during recycling breaks down their molecular chains, resulting in lower quality materials."

    Trade secrets: industry's publishing dilemma

    Brian Owens
    S2-S5页
    查看更多>>摘要:Academic research might lay the groundwork for modern technology, butthe products we use daily are often shaped by innovations from corporate labs. Unlike in academia, where publishing is central to progress, corporate research tends to prioritize secrecy - protect-ing discoveries to maintain a competitive edge. That is not to say that companies don't disseminate the results of their research. Results are often shared in company annual reports, investor prospectuses and white papers. And US publicly traded firms producearound 30,000 peer-reviewed scientific publications a year, says Dror Shvadron, a researcher at the University of Toronto in Canada who studies how companies approach scientific research. "It's a big activity that firms are involved in," he says.

    SWARMS OF AI ROBOTS COULD EXTEND HUMAN CAPABILITIES

    S8-S9页
    查看更多>>摘要:A swarm of tiny, cylindrical robots on wheels that move in sync with the wave of a hand or a flick of the finger was unveiled in Tokyo in 2024. Small, independent machines that collectively behave like schools of fish, swarm robots can arrange themselves into patterns and coordinate to manipulate larger objects. They are examples of Al-imbued robots that might help us to further push beyond the physical boundaries of the human body. For example, a racket or violin are tools that can serve as an extension of our bodies when playing tennis or making music - but swarms of robots might allow us to do so much more. Shigeo Yoshida is a principal investigator in the Integrated Interaction Group at OMRON SINIC X (OSX), a Tokyo company spun off from OMRON to establish a research base for technology to meet social needs. He is extending that research by investigating whether a system as disjointed as a swarm of robots can act as an extension of the human body - even when they are physically remote from the body.

    THE HIDDEN ROLE OF GUT FUNGI IN NEURODEGENERATIVE DISEASES

    a5-a6页
    查看更多>>摘要:How does the brain interact with the gut microbiome? The microbiome, together with the metabolites it generates, educates and trains the immune system in ways that affect the entire body. We are in effect a 'holobiont' - an ecosystem hosting the microbial inhabitants that we have co- evolved with. We have evolved to respond to cues from these microbes, and they have evolved to respond to cues from us. Some cues from the microbiome support the healthy functioning of the central nervous system. When signals from the gut microbiome are disrupted, this can interfere with the integrity of various components of the central nervous system, potentially triggering harmful neuroinflammation and neurodegeneration.

    BREAKING BARRIERS TO BIOTECH TRANSLATION IN CHINA

    a7-a8页
    查看更多>>摘要:In recent years a string of important and innovative cancer drugs developed by Chinese companies have been approved by the US Food and Drug Administration (FDA). The approvals provided immediate access to the world's largest and most profitable pharmaceutical market, and boosted the credibility and value of Chinese companies behind the new therapies. These drugs also marked a turning point for China's industry which has stepped up its biotechnology R&D efforts, according to a new Chinese-language report, The Blue Book on the Translation of China's Biotechnology Achievements.

    Science Inc.

    Bec Crew
    S1-S1页
    查看更多>>摘要:As the United States cuts billions of dollars in federal funds for research, the role of the private sector in driving and supporting science and innovation has been put under the spotlight. Could US pharmaceutical giants support drug- or vaccine-development projects that have lost their funding? Will tech and engineering firms use their clout to advance defunded research in green energy? And if companies do fill the fundinggap, how might the priorities of research projects shift to meet business goals and pressures? We can look at the landscape for clues. Research publishing by firms seems to be on the wane, which could reflect a preference for keeping discoveries close to the chest. But there are ways to incentivize the private sector to publish peer-reviewed research - if that is a desired policy goal (see page S2). China, meanwhile, which lags behind the United States for company research published in the Nature Indexjournals but is catching up fast, is rapidly developing how its private sector works with academia. Leaps in highly competitive technologies such as artificial intelligence and electric vehicles also point to a key difference between its approach and that of the United States (see page S6): the Chinese government is much more likely to shoulder the financial risk of such ventures.

    EXPLORING HOW CELLS INTERACT WITH BACTERIOPHAGES IN THE GUT

    a2-a3页
    查看更多>>摘要:What originally drew you to virology? I've long been interested in viruses that infect humans and how they interact with the bacteria in our guts. During my postdoctoral training, I began to examine viruses that cause diarrhoea after infecting human cells, such as norovirus. I became intrigued by the idea that the bacterial microbiota can suppress or promote viral infections. When I started my own independent research programme, I decided that a key focus for my lab would be viruses that infect or reside in the gut, including bacteriophages. What are bacteriophages? Bacteriophages are viruses that infect bacteria. Different species have different lifecycles. Some infect a bacterium and kill it after replicating, whereas others become integrated into the bacterial genome and influence a bacteria's activity in that way. Because these viruses don't directly infect human cells, potential interactions between bacteriophages and human cells have mostly been ignored. However, we're convinced that it's important to understand not only how bacteriophages and gut bacteria interact, but also how bacteriophages affect human gut cells.

    VIRAL GUT COMPONENTS COULD INFLUENCE IBD FLARE-UPS IN CHILDREN

    a3-a5页
    查看更多>>摘要:Why is researching IBD in children so important? The incidence of inflammatory bowel disease (IBD) is rising globally, and this is becoming particularly stark in the Middle East and North Africa. The causes of IBD are still unclear, but they likely include a combination of genetic and environmental factors with immune system dysfunction. For reasons that are not yet clear, younger patients tend to experience more severe versions of IBD that require aggressive treatment. So the earlier we diagnose IBD and intervene, the better it is for their long-term health. I firmly believe that we cannot fully understand disease pathophysiology without looking at the microbiome and its composition.