首页|EXPLORING HOW CELLS INTERACT WITH BACTERIOPHAGES IN THE GUT
EXPLORING HOW CELLS INTERACT WITH BACTERIOPHAGES IN THE GUT
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NETL
NSTL
What originally drew you to virology? I've long been interested in viruses that infect humans and how they interact with the bacteria in our guts. During my postdoctoral training, I began to examine viruses that cause diarrhoea after infecting human cells, such as norovirus. I became intrigued by the idea that the bacterial microbiota can suppress or promote viral infections. When I started my own independent research programme, I decided that a key focus for my lab would be viruses that infect or reside in the gut, including bacteriophages. What are bacteriophages? Bacteriophages are viruses that infect bacteria. Different species have different lifecycles. Some infect a bacterium and kill it after replicating, whereas others become integrated into the bacterial genome and influence a bacteria's activity in that way. Because these viruses don't directly infect human cells, potential interactions between bacteriophages and human cells have mostly been ignored. However, we're convinced that it's important to understand not only how bacteriophages and gut bacteria interact, but also how bacteriophages affect human gut cells.
NETL
NSTL
