首页期刊导航|The Journal of Emergency Medicine
期刊信息/Journal information
The Journal of Emergency Medicine
Pergamon Press
The Journal of Emergency Medicine

Pergamon Press

0736-4679

The Journal of Emergency Medicine/Journal The Journal of Emergency Medicine
正式出版
收录年代

    Incidence, Clinical Characteristics, Risk Factors and Outcomes of Acute Coronary Syndrome in Patients With COVID-19: Results of the UMC-19-S10(10)

    Alquezar-Arbe, AitorMiro, OscarGonzalez del Castillo, JuanJimenez, Sonia...
    12页
    查看更多>>摘要:Background: There is a lack of knowledge about the real incidence of acute coronary syndrome (ACS) in patients with COVID-19, their clinical characteristics, and their prognoses. Objective: We investigated the incidence, clinical characteristics, risk factors, and outcomes of ACS in patients with COVID-19 in the emergency department. Methods: We retrospectively reviewed all COVID-19 patients diagnosed with ACS in 62 Spanish emergency departments between March and April 2020 (the first wave of COVID-19). We formed 2 control groups: COVID-19 patients without ACS (control A) and non-COVID-19 patients with ACS (control B). Unadjusted comparisons between cases and control subjects were performed regarding 58 characteristics and outcomes. Results: We identified 110 patients with ACS in 74,814 patients with COVID-19 attending the ED (1.48% [95% confidence interval {CI} 1.21-1.78%]). This incidence was lower than that observed in non-COVID19 patients (3.64% [95% CI 3.54-3.74%]; odds ratio [OR] 0.40 [95% CI 0.33-0.49]). The clinical characteristics of patients with COVID-19 associated with a higher risk of presenting ACS were: previous coronary artery disease, age >= 60 years, hypertension, chest pain, raised troponin, and hypoxemia. The need for hospitalization and admission to intensive care and in-hospital mortality were higher in cases than in control group A (adjusted OR [aOR] 6.36 [95% CI 1.8422.1], aOR 4.63 [95% CI 1.88-11.4], and aOR 2.46 [95% CI 1.15-5.25]). When comparing cases with control group B, the aOR of admission to intensive care was 0.41 (95% CI 0.210.80), while the aOR for in-hospital mortality was 5.94 (95% CI 2.84-12.4). Conclusions: The incidence of ACS in patients with COVID-19 attending the emergency department was low, around 1.48%, but could be increased in some circumstances. Patients with COVID-19 with ACS had a worse prognosis than control subjects with higher in-hospital mortality. (C) 2021 Elsevier Inc. All rights reserved.

    The Relative Efficacy of Seven Skeletal Muscle Relaxants. An Analysis of Data From Randomized Studies

    Abril, LorenaZamora, CristianCordero, MariaWilliams, Andrew R....
    7页
    查看更多>>摘要:Background: Low back pain (LBP) causes 2.6 million visits to U.S. emergency departments (EDs) annually. These patients are often treated with skeletal muscle relaxants (SMRs). Objectives: The goal of this study was to determine whether efficacy of SMRs is associated with age, sex, or baseline LBP severity. Methods: This was a planned analysis of data from 4 randomized studies of patients with acute nonradicular LBP. Patients were enrolled during an ED visit and followed-up 1 week later. The primary outcome was improvement in the Roland-Morris Disability Questionnaire (RMDQ) between ED discharge and the 1-week follow-up. We compared the change in RMDQ among 8 groups: placebo, baclofen, metaxalone, tizanidine, diazepam, orphenadrine, methocarbamol, and cyclobenzaprine. All patients also received a nonsteroidal anti-inflammatory drug. We performed analysis of variance to determine statistically significant differences between medications and linear regression to determine the association of age, sex, and baseline severity with the primary outcome. Results: The mean improvement in RMDQ per group was placebo 10.5 (95% confidence interval [CI] 9.5-11.5), baclofen 10.6 (95% CI 8.6-12.7), metaxalone 10.3 (95% CI 8.1-12.4), tizanidine 11.5 (95% CI 9.5-13.4), diazepam 11.1 (95% CI 9-13.2), orphenadrine 9.5 (95% CI 7.4-11.5), methocarbamol 8.1 (95% CI 6.1-10.1), and cyclobenzaprine 10.1 (95% CI 8.3-12). The between-group differences were not statistically significantly different. Results were similar regardless of age, sex, and baseline severity. Higher baseline RMDQ was associated with greater clinical improvement (B coefficient 5.7, p < 0.01). Adverse medication effects were more common with cyclobenzaprine than with placebo (p < 0.01). Conclusions: Among patients in the ED with acute LBP treated with a nonsteroidal anti-inflammatory drug, SMRs do not improve outcomes more than placebo. Neither age, sex, nor baseline impairment impacts these results. (C) 2021 Elsevier Inc. All rights reserved.

    Results of Reduction of Dislocated Prosthetic Hips in the Emergency Department

    Blokland, ArrienVan den Akker, VeroniqueVan der Poort, CecileSomford, Matthijs...
    6页
    查看更多>>摘要:Background: Dislocation of total hip arthroplasty (dTHA) is a commonly encountered complication in the emergency department (ED). Several studies have been conducted that describe the overall success rate after reduction in the ED, however, all were small in sample size. Objectives: The aim of the study was to assess the success rate of reduction of dTHA by emergency physicians in the ED under procedural sedation (PSA). Methods: Patients who presented to the ED with a dislocated prosthetic hip were eligible for inclusion. We performed a retrospective cohort study assessing success rate. Secondary parameters included time to reduction, discharge rate from the ED, and complication rate. Results: There were 305 patients analyzed. Of these, 31 were excluded due to hemi-arthroplasty and 25 because they went primarily for reduction in the operating room. In total, 249 patients were included. Of 249 attempted reductions in the ED, 230 (92%, 95% confidence interval [CI] 89-96%) were successful. Seventy-one cases (28.5%, 95% CI 22.9-34.2%) were discharged from the ED after successful reduction. Six cases (2.4%, 95% CI 0.2-2.6%) experienced complications related to PSA and three cases (1.2%, 95% CI 0.5-4.3%) experienced complications related to reduction. Conclusion: Reduction of a dTHA can be performed safely in the ED under PSA by emergency physicians with a high rate of success. (C) 2021 Elsevier Inc. All rights reserved.

    Not All Testers are Admitters: An Analysis of Emergency Physician Resource Utilization and Consultation Rates

    Antkowiak, Peter S.Lee, TerranceChiu, David T.Stenson, Bryan A....
    7页
    查看更多>>摘要:Background: Variability exists in emergency physician (EP) resource utilization as measured by ordering practices, rate of consultation, and propensity to admit patients. Objective: To validate and expand upon previous data showing that resource utilization as measured by EP ordering patterns is positively correlated with admission rates. Methods: This is a retrospective study of routinely gathered operational data from the ED of an urban academic tertiary care hospital. We collected individual EP data on advanced imaging, consultation, and admission rates per patient encounter. To investigate whether there might be distinct groups of practice patterns relating these 3 resources, we used a Gaussian mixture model, a classification method used to determine the likelihood of distinct subgroups within a larger population. Results: Our Gaussian mixture model revealed 3 distinct groups of EPs based on their ordering practices. The largest group is characterized by a homogenous pattern of neither high or low resource utilization (n = 37, 27% female, median years' experience: 6 [interquartile ratio {IQR} 3-18]; rates of advanced imaging, 38.9%; consultation, 45.1%; and admission 39.3%), with a modest group of low-resource users (n = 15, 60% female, median years' experience: 6 [IQR 5-14]; rates of advanced imaging, 37%; consultation, 42.6%; and admission 37.3%), and far fewer members of a high-resource use group (n = 6, 0% female, median years' experience: 6 [IQR 4-16]; rates of advanced imaging, 42.2%; consultation, 45.8%; and admission 40.6%). This variation suggests that not "all testers are admitters," but that there exist wider practice variations among EPs. Conclusions: At our academic tertiary center, 3 distinct subgroups of EP ordering practices exist based on consultation rates, advanced imaging use, and propensity to admit a patient. These data validate previous work showing that resource utilization and admission rates are related, while demonstrating that more nuanced patterns of EP ordering practices exist. Further investigation is needed to understand the impact of EP characteristics and behavior on throughput and quality of care. (C) 2022 Elsevier Inc. (C)) 2021 Published by Elsevier Inc.

    An Immaculate Deception: Persistently Elevated Serum beta-Hcg in Metastatic Signet Ring Cell Gastric Adenocarcinoma

    LaFree, AndrewHryniewicki, Adam T.
    5页
    查看更多>>摘要:Background: Persistent elevations in beta-human chorionic gonadotropin (beta-hCG) can be an ominous sign of both trophoblastic and non-trophoblastic malignancies. The absence of a clearly identified etiology of beta-hCG elevation warrants pursuit of further diagnostic testing to determine the source of ectopic beta-hCG. Case Report: A virginal 26-year-old woman with past medical history significant for persistently elevated beta-hCG presented to our Emergency Department with shortness of breath, pleuritic chest pain, nausea, and vomiting, and was found to have widely metastatic gastric signet ring cell adenocarcinoma. Why Should an Emergency Physician Be Aware of This?: Although elevated serum beta-hCG is a generally a marker of pregnancy, beta-hCG elevation without clear etiology necessitates ruling out other insidious processes. Failure to maintain and pursue a broad differential in the context of unexplained elevations of beta-hCG can result in catastrophic missed or delayed diagnosis. (C) 2022 Published by Elsevier Inc.

    Necrotizing Soft Tissue Infections (NSTI): Pearls and Pitfalls for the Emergency Clinician

    Pelletier, JessicaGottlieb, MichaelLong, BritPerkins, John C., Jr....
    12页
    查看更多>>摘要:Background: Skin and soft tissue infections are common emergency department (ED) presentations. These infections cover a wide spectrum of disease, from simple cellulitis to necrotizing fasciitis. Despite the commonality, a subset of skin and soft tissue infections known as necrotizing soft tissue infections (NSTIs) can cause significant morbidity and mortality. Objective: This review evaluates the current evidence regarding the presentation, evaluation, and management of NSTI from the ED perspective. Discussion: NSTIs are commonly missed diagnoses. History and physical examination findings are inconsistent, and the risk factors for this high mortality disease are common amongst ED populations. Laboratory evaluation and the Laboratory Risk in Necrotizing Fasciitis (LRINEC) score is helpful but is insufficient to rule out the disease. Imaging modalities including ultrasound, computed tomography, and magnetic resonance imaging are highly sensitive and specific, but may delay definitive management. The gold standard for diagnosis includes surgical exploration. Surgical intervention and empiric broad-spectrum antibiotic coverage are the foundations of treatment. Adjuvant therapies including hyperbaric oxygen and intravenous immunoglobulin have not yet been proven to be beneficial or to improve outcome. Conclusion: NSTIs are associated with significant morbidity and mortality. Knowledge of the history, examination, evaluation, and management is vital for emergency clinicians. (C) 2021 Published by Elsevier Inc.

    Artificial Intelligence in Emergency Medicine: Benefits, Risks, and Recommendations

    Derse, Arthur R.Basford, Jesse B.Larkin, Gregory LukeMoskop, John C....
    8页
    查看更多>>摘要:Background: Artificial intelligence (AI) can be described as the use of computers to perform tasks that formerly required human cognition. The American Medical Association prefers the term 'augmented intelligence' over 'artificial intelligence' to emphasize the assistive role of computers in enhancing physician skills as opposed to replacing them. The integration of AI into emergency medicine, and clinical practice at large, has increased in recent years, and that trend is likely to continue. Discussion: AI has demonstrated substantial potential benefit for physicians and patients. These benefits are transforming the therapeutic relationship from the traditional physician-patient dyad into a triadic doctor-patient-machine relationship. New AI technologies, however, require careful vetting, legal standards, patient safeguards, and provider education. Emergency physicians (EPs) should recognize the limits and risks of AI as well as its potential benefits. Conclusions: EPs must learn to partner with, not capitulate to, AI. AI has proven to be superior to, or on a par with, certain physician skills, such as interpreting radiographs and making diagnoses based on visual cues, such as skin cancer. AI can provide cognitive assistance, but EPs must interpret AI results within the clinical context of individual patients. They must also advocate for patient confidentiality, professional liability coverage, and the essential role of specialty-trained EPs. (C) 2022 Published by Elsevier Inc.

    Comparison of Commercial Versus Homemade Models for Teaching Ultrasound-Guided Peripheral IV Placement

    Sajadi, KarimaCrosby, LeslieYu, MelissaLongenbach, James...
    8页
    查看更多>>摘要:Background: Various commercially available and do-it-yourself (DIY) models are used to teach emergency medicine (EM) residents and medical students ultrasound (US)-guided i.v. insertion. Expensive commercial models degrade over time, but DIY models are inexpensive, easily prepared, and readily discarded. Objective: We tested the hypothesis that DIY models are equally effective as commercial models for teaching US-guided i.v. insertion, and using a controlled trial to subjectively evaluate how well DIY models and commercially manufactured models compare with human tissue both tactilely and sonographically. Methods: We tested three models for US-guided i.v. teaching-a commercially available model US training block model, a homemade tofu model, and a homemade gelatin model. All three models were compared with US-guided i.v. insertion involving human tissue. Study participants were EM residents and EM attendings experienced in US-guided i.v. placement in real patients. After practicing peripheral i.v. placement under US guidance using the three media, participants at various levels of training and experience with US-guided i.v. insertion subjectively described how each media compared tactilely and sonographically, which model was most similar to a live human overall, and which model was best for instructing learners. Results: The overall score (sum of visual and sonographic scores) for the gelatin model was significantly higher than either of the other models, indicating that the gelatin model was evaluated as most approximate to the anatomy of a human compared with the other models. Conclusions: Inexpensive homemade alternatives to commercial simulators can be realistic and effective surrogates for learning US-guided peripheral i.v. placement. (C) 2022 Published by Elsevier Inc.

    Ethics, Personal Responsibility and the Pandemic: A New Triage Paradigm

    Iserson, Kenneth, V
    5页
    查看更多>>摘要:Background: How much of a role should personal responsibility play in triage criteria? Because voluntarily unvaccinated people are not fulfilling their societal obligations during a pandemic, the ethical principle of justice demands that they reap the egalitarian consequences. These consequences could include lower priority for care, an increasing number of employer and government mandates, and restrictions to entering many entertainment venues. Discussion: Voluntarily unvaccinated individuals increase the chance that the COVID-19 virus will mutate and spread, endangering the entire population, but especially those who cannot get vaccinated for medical reasons, children for whom vaccines have yet to be approved, and older adult and immunocompromised people for whom the vaccine is less effective. When voluntarily unvaccinated individuals seek medical treatment for COVID-19 (94% of patients with COVID-19 in U.S. intensive care units), they use resources needed for those with non-COVID-related illnesses. Conclusions: A method to balance resource allocation between those patients who refuse vaccination and patients who need the same health care resources is necessary. An ethical solution is to give those who are voluntarily unvaccinated a lower priority for admission and for the use of other health care resources. Current in-hospital triage models can easily be modified to accomplish this. This substantive change in practice may encourage more people to get vaccinated. (C) 2021 Published by Elsevier Inc.

    They Also Serve Who Only Sit and Answer COVID-19 Hotline Telephones

    Ratzan, Richard M.
    3页