查看更多>>摘要：An efficient radical chlorosulfonylation of allenes was disclosed and vinylsulfones were prepared smoothly under mild conditions. By using sodium sulfinates as radical precursors, iron(III) chloride hexahydrate (FeCl3 center dot 6H(2)O) as oxidant and chloride source, allenes were converted into (E)-alpha-chloromethyl vinylsulfones via regioselective 1,2-radical difunctionalization process in moderate to good yields. (C) 2022 Elsevier Ltd. All rights reserved.
查看更多>>摘要：While 1,2-regioselective difunctionalizations of alkenes are well developed, their migratory difunctionalization of alkenes remains comparatively under-researched. Herein, we report a nickel-catalyzed, divergent, solvent-controlled 1,1- or 1,3-regioselective benzylboration of allylbenzenes, that provides efficient access to primary and secondary alkyl boronates. The mild reaction conditions of these transformations allow good regioselectivity and wide functional group tolerance. (C) 2022 Elsevier Ltd. All rights reserved.
查看更多>>摘要：An AIE-active pyran derivative bearing bromine, but no alkyl chains or amide units was found to be able to gelate organic solvent aided by the halogen-assisted balanced intermolecular pi-pi interactions. Moreover, the pyran derivative exhibits tri-colored high-contrast mechanochromism based on the transition between monomer and different pi dimers. (C) 2022 Elsevier Ltd. All rights reserved.
Azeredo, Juliano BraunCandido Thedy, Maria EduardaGodoi, MarceloKeller, Mateus Henrique...
6页
查看更多>>摘要：Herein, we describe an efficient, fast, mild and sustainable protocol for the oxidation of thiols using Urea Hydrogen Peroxide (UHP) to give the corresponding disulfides in good to excellent yields. The methodology uses polysorbate 80 as a greener solvent and catalyst which was, for the first time, recovered from the reaction medium and reused. (C) 2022 Elsevier Ltd. All rights reserved.
查看更多>>摘要：A Lewis acid-catalyzed cyclization of N-(p-methoxyphenyl)-3-phenylpropionamide with N-thiocyanosuccinimide has been accomplished under mild conditions. Thus, a series of thiocyanato-containing spirocyclohexadienones was obtained in moderate to excellent yields with a good functional group tolerance and a wide range of substrates. It provides an alternative approach for the synthesis of functionalized spirocyclohexadienones. (C) 2022 Published by Elsevier Ltd.
查看更多>>摘要：A novel and facile metal-free method for the green synthesis of 2-amino-4-arylthiazole derivatives through the three-component cascade reaction of aromatic methyl ketones, elemental sulfur and cyanamide is reported. One C-N bond and two C-S bonds were formed in one-pot protocol without using catalysts. (C) 2022 Elsevier Ltd. All rights reserved.
查看更多>>摘要：Tetraphenylethylene with electron withdrawing pyridinium cations and cyano groups were designed and synthesized. Cyanoprobe 2 has a typical Aggregate Induced Emission effect under physiological conditions, while cation probe 1 cannot aggregate luminescence due to its higher hydrophilicity. When interacting with aromatase, probe 1 showed obvious fluorescence change, but probe 2 did not. Under the same conditions, or even under the interference of various factors, probe 1 can recognize aromatase with high sensitivity. Probe 1 can rapidly light up aromatase-expressing cells. Probe 1 have the properties of aromatase inhibitors, which can inhibit the growth of tumor cells. The design ideas of cationic AIE fluorescent probes in this paper are expected to be applied to other targets. (C) 2022 Elsevier Ltd. All rights reserved.
查看更多>>摘要：Here we show a novel colorimetric sensor system with a photo-induced colorimetric reaction of N,N'-bis[2-(trimethylammonium)ethyl]-1,8:4,5-naphthalenetetracarboxdiimide (TENDI) to detect and quantify carboxylate derivatives. In the presence of CH3COONa, TENDI aqueous solution under UV irradiation shows a photo-induced colorimetric reaction, which is due to the production of naphthalenediimide (NDI)-based radical anions whose absorbance peaks appear at around 400-600 nm. In contrast, no color changes are observed in the cases of diverse inorganic salts. In addition, TENDI shows another ability to discriminate the structural features of carboxylate derivatives by color tone. Moreover, interestingly, the Hill equation can approximate the relationship between carboxylate concentrations and absorbance values on the maximum absorbance wavelengths of the absorbance peaks due to the NDI-radical anions. (C) 2022 Elsevier Ltd. All rights reserved.
查看更多>>摘要：Asymmetric 2,7-di-tert-butyl-10b,10c-dimethyl-2',3'-dimethyl-pyrazino[2,3-e]dihydropyrene (DMPZ-DHP) was prepared by the annulation of diamino dihydropyrene with 2,3-butanedione. Optical resolution was achieved using chiral high-performance liquid chromatography systems after the photoisomerization of DMPZ-DHP to DMPZ-metacyclophane-diene (MCPD), and its Kuhn's anisotropy factor (g = Delta epsilon/epsilon) was determined to be approximately 1.0 e(-3) at 550 nm. [S]- and [R]-DMPZ-DHP were irradiated with 550nm left and right circularly polarized light (CPL), and photoisomerization was found to proceed more rapidly upon irradiating the [S]-isomer with right-CPL than with left-CPL and upon irradiating the [R]-isomer with left-CPL than with right-CPL. This suggests that CPL can be detected and analyzed using asymmetric DMPZ-DHP. (C) 2022 Published by Elsevier Ltd.
NSTL
Elsevier