查看更多>>摘要：Fish, bivalve mollusks, other marine animals and algae that are normally consumed safely may become toxic and thereby cause human intoxication. The spotty and unpredictable occurrence of the toxicity lay obstacles to securing enough material needed to elucidate toxin structures and identify the primary origins. Aggravating the problem of tiny sample amounts, toxins are often large and highly complex. A typical example is explained by the ciguatera study where structural determination was achieved with 0.35 mg of ciguatoxin isolated from 124 kg of moray ell livers collected over 10 years and with 20 mg of maito-toxin accumulated by culturing a slow-growing dino-flagellate over 10 years. The study also opened a door to numerous dinoflagellate toxins that accumulate in fish and shellfish via food chain. Additionally, tetrodo-toxin in pufferfish was revealed to be of bacterial origin.
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