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Journal of Aerosol Science
Pergamon Press
Journal of Aerosol Science

Pergamon Press

0021-8502

Journal of Aerosol Science/Journal Journal of Aerosol ScienceSCIISTPEI
正式出版
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    Modeling particle-particle binary coagulation rate constants for spherical aerosol particles at high volume fractions using Langevin Dynamics simulations

    Suresh, VikramLiu, ZhiboPerry, ZacharyGopalakrishnan, Ranganathan...
    17页
    查看更多>>摘要:Effect of volume-fraction and particle-particle hydrodynamic interactions on the coagulation rate of particles are investigated. Particle coagulation is modeled using Langevin Dynamics (LD) based trajectory simulations of N mono-sized spherical particles in a periodic domain. The extended Kirkwood-Risemann approach (J. Fluid Mechanics 855, 535 (2018)) is invoked to compute particle-particle hydrodynamic interactions whose effect is parameterized as a function of the momentum Knudsen number (Kn). The results are summarized as a model for coagulation rate constant (beta ij) that depends on the diffusive Knudsen number (KnD) used in prior work to parameterize coagulation in the dilute regime (Aerosol Sci. Tech. 45, 1499 (2011)), Kn and particle volume-fraction eta v. In the absence of hydrodynamic interactions, it is observed that the coagulation rate constant in the continuum limit for mass transfer (KnD -> 0) is significantly enhanced by a factor of-80 at eta v <- 0.3 due to particle crowding. While considering hydrodynamic interactions for eta v & GE; 0.05, we use a screening distance around each particle that scales inversely with eta v beyond which the contribution of farther neighbors is neglected owing to the rapid decay of hydrodynamic interactions with distance. We also present new LD calculations of beta ij and elucidate the dependence of the same on Kn1 and the particle radii ratio theta r for the coagulation of two particles in the dilute limit eta v & RARR; 0. It is observed that the reduction of beta ij becomes significant as Kn1 & RARR; 0: at the lowest momentum Knudsen number considered (Kn1 = 0.1): beta ij is reduced by a factor of-10 for equally sized particles (theta r = 0.5). At high KnD,Kn1, the particle size disparity is not significant, and it is seen that beta ij matches hard sphere predictions, indicating the insignificant contributions by hydrodynamic interactions. A series of animations of 2 particle simulations are presented as part of the Supplemental Information to illustrate the role of hydrodynamic interactions in particle coagulation. Computational results are summarized as regressions for convenient incorporation into particle/droplet growth sectional models.

    Aerosolization triggers immediate antibiotic resistance in bacteria

    Smith, Brooke L.King, Maria D.
    12页
    查看更多>>摘要:Antibiotic resistance poses a threat in many institutions including hospitals, meat processing facilities and other agricultural and occupational entities. The goal of this research is to uncover how bacteria react to environmental conditions including aerosolization and delineate factors that trigger expression of antibiotic resistance genes (ARGs) using the laboratory strain Escherichia coli (E. coli) MG 1655 as surrogate bacterium. Fresh mid-log phase bacterial suspensions were aerosolized at different environmental conditions for 5 different time durations into a sterile chamber and collected using a bioaerosol collector. Each sample was analyzed based on its response to each environmental factor by antibiotic susceptibility testing and polymerase chain reaction (PCR) using specific primers to target ARGs. Strong resistance was detected to cell wall and protein synthesis inhibitors Cephalothin, and Gentamicin after 5 min compared to 30 min and 45 min of aerosolizations in reference to viable cell concentrations. Resistance to the highest number of antibiotics was detected in the shortest aerosolization samples while exposure for longer aerosolization durations caused an increased amount of stress which bacteria could not alleviate, indicating the involvement of different mechanisms to respond to short-term and longterm exposures. A small amount of resistance was detected after intermediate durations of aerosolization, maybe due to a transient response of the cells to compensate for mechanical, osmotic and other stresses during aerosolization. This study is the first to demonstrate that aerosolization triggers antibiotic resistance within minutes in E. coli.

    The dependence of the drag force of a moving aerosol particle on its nature of molecule-surface interaction

    Sograbi, T. V.Chernyak, V. G.
    12页
    查看更多>>摘要:The dependence of the drag force on the nature of molecule-surface interaction is studied in the case of a low-speed flow of rarefied gas around a spherical particle. Expressions for the drag force and thermal polarization are obtained for a near-free molecule regime and an arbitrary scattering kernel. We used the model kinetic equation with a third-order collision integral obtained from the requirement that the moments of the Boltzmann and approximating collision integrals be equal. Numerical calculations using established scattering kernel models are performed. The numerical values of the accommodation parameters for all the used models are obtained from a comparison of the theoretical results with Millikan's data regarding watch oil drops in air.

    A sheathed virtual impactor-Microseparator for improved separation of sub- and supercritical sized particles

    Wang, PanYuan, ShouqiOppong, Paul KwabenaYang, Ning...
    10页
    查看更多>>摘要:In the separation process of airborne microbial particles, a typical virtual impactor with sheath flow is effective to lower the critical diameter and minimize wall loss. However, a considerable fraction of undesired subcritical particles smaller than the critical diameter are gathered in the minor flow. To address this issue, this article presents a novel microseparator to reduce subcritical particle content while preserving the typical virtual impactor's advantages. The microseparator made of a microfluidic chip adopts a core-aerosol-sheath configuration in which the core and sheath flows raised from clean airflow confine the distribution of microparticles in the aerosol flow towards the core region of the microchannel but away from the center axis. Such configuration effectively decreases the subcritical particle content in the minor flow. The improvement of the proposed microseparator is quantified by comparing the performance with the typical virtual impactor numerically and experimentally at the same critical diameter. At the critical diameters of 0.35 mu m, 0.42 mu m, 0.52 mu m, and 0.6 mu m, we find that, firstly, the ratios of subcritical particle content to total particle content (Csp) of our device are 5.24%, 4.74%, 12.34%, and 7.76% smaller than those of typical virtual impactor, respectively. Secondly, the corresponding reduction ratios of subcritical particle (Rsp) of our device are 25.87%, 21.20%, 40.31%, and 33.92%. Lastly, the maximum wall loss of the proposed microseparator in the collection probe is slightly smaller than the typical one, while the operation range of minor flow is enlarged with the premise of maintaining low subcritical particle collection efficiency.

    Efficacy of single pass UVC air treatment for the inactivation of coronavirus, MS2 coliphage and Staphylococcus aureus bioaerosols

    Snelling, William J.Afkhami, ArsalanTurkington, Hannah L.Carlisle, Claire...
    12页
    查看更多>>摘要:There is strong evidence that SARS-CoV-2 is spread predominantly by airborne transmission, with high viral loads released into the air as respiratory droplets and aerosols from the infected subject. The spread and persistence of SARS-CoV-2 in diverse indoor environments reinforces the urgent need to supplement distancing and PPE based approaches with effective engineering measures for microbial decontamination - thereby addressing the significant risk posed by aerosols. We hypothesized that a portable, single-pass UVC air treatment device (air flow 1254 L/min) could effectively inactivate bioaerosols containing bacterial and viral indicator organisms, and coronavirus without reliance on filtration technology, at reasonable scale. Robust experiments demonstrated UVC dose dependent inactivation of Staphylococcus aureus (UV rate constant (k) = 0.098 m2/J) and bacteriophage MS2, with up to 6-log MS2 reduction achieved in a single pass through the system (k = 0.119 m2/J). The inclusion of a PTFE diffuse reflector increased the effective UVC dose by up to 34% in comparison to a standard Al foil reflector (with identical lamp output), resulting in significant additional pathogen inactivation (1-log S. aureus and MS2, p < 0.001). Complete inactivation of bovine coronavirus bioaerosols was demonstrated through tissue culture infectivity (2.4-log reduction) and RT-qPCR analysis - confirming single pass UVC treatment to effectively deactivate coronavirus to the limit of detection of the culture-based method. Scenario-based modelling was used to investigate the reduction in risk of airborne person-to-person transmission based upon a single infected subject within the small room. Use of the system providing 5 air changes per hour was shown to significantly reduce airborne viral load and maintain low numbers of RNA copies when the infected subject remained in the room, reducing the risk of airborne pathogen transmission to other room users. We conclude that the application of single-pass UVC systems (without reliance on HEPA filtration) could play a critical role in reducing the risk of airborne pathogen transfer, including SARS-CoV2, in locations where adequate fresh air ventilation cannot be implemented.

    Detection of SARS-CoV-2 in the air in Indian hospitals and houses of COVID-19 patients

    Moharir, Shivranjani C.Thota, Sharath ChandraGoel, ArushiThakur, Bhuwaneshwar...
    10页
    查看更多>>摘要:To understand the transmission characteristics of severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) through air, samples from different locations occupied by coronavirus disease (COVID-19) patients were analyzed. Three sampling strategies were used to understand the presence of virus in the air in different environmental conditions. In the first strategy, which involved hospital settings, air samples were collected from several areas of hospitals like COVIDintensive-care units (ICUs), nurse-stations, COVID-wards, corridors, non-COVID-wards, personal protective equipment (PPE) doffing areas, COVID rooms, out-patient (OP) corridors, mortuary, COVID casualty areas, non-COVID ICUs and doctors' rooms. Out of the 80 air samples collected from 6 hospitals from two Indian cities-Hyderabad and Mohali, 30 samples showed the presence of SARS-CoV-2 nucleic acids. In the second sampling strategy, that involved indoor settings, one or more COVID-19 patients were asked to spend a short duration of time in a closed room. Out of 17 samples, 5 samples, including 4 samples collected after the departure of three symptomatic patients from the room, showed the presence of SARS-CoV-2 nucleic acids. In the third strategy, involving indoor settings, air samples were collected from rooms of houses of home-quarantined COVID-19 patients and it was observed that SARS-CoV-2 RNA could be detected in the air in the rooms occupied by COVID-19 patients but not in the other rooms of the houses. Taken together,

    Multi-mechanism theory of aerosol capture by fibrous filters, including fiber diameter/orientation dispersity and particle morphology effects. Preliminary tests vs. data for mobility-selected submicron particles

    Rosner, Daniel E.Arias-Zugasti, Manuel
    15页
    查看更多>>摘要:In Paper I (Sep. Purif. Technol. 257 (2021) 117676) we showed that a semi-analytic, multi mechanism expression for the single-fiber capture fraction, ncap,SF, (derived using asymptotically valid approximations: Re-f < 0.4, Pe(f) & raquo; 1, R & laquo; 1, R center dot Pe(f)(1/3) arbitrary and Stk(p) <= Stk(pcrit)), facilitates a deterministic-, pseudo-continuum aerosol population-balance (PB-) approach to predicting fibrous filter performance. There we explicitly considered "deep "(L-f/d(f,g )& raquo; 1), low solidity idealized fibrous filters (FFs) challenged by polydispersed aerosols-especially single mode log-normal (LN) ASDs of modest spread captured by a spatially uniform array of fibers of a single diameter in crossflow. However, realistic fibrous filter media often possess a LN distribution of fiber diameters, as well as a near-Gaussian orientation distribution narrowly spread about normal incidence (theta = pi/2). Moreover, even if this were not so, there would be meso-scale departures from a uniform average fiber solid fraction. We show here that our tractable aerosol PBE-approach to idealized FF performance (Paper I) can be generalized to incorporate these particular structural features of commercially available fibrous filter media. But, to clarify whether these generalizations are likely to be useful, if not fully sufficient, for practical circumstances, it is also necessary to compare such methods/predictions against selected sets of well-defined experimental results. We initiate this program here, having chosen the recent experiments of Kang et al. (2019) carried out using a commercially available fiberglass filter with L-f/d(f,g )asymptotic to 300, mean solid fraction of 0.039, and d(f,g) = 2.5 mu m, successively challenged by mobility-selected KCl(s) particles (with diameters between ca. 20 and 600 nm) at the carrier gas velocities of 15 and 10 cm/s-capture conditions dominated by the transport mechanism of Brownian diffusion and convection, with "interception "(associated with non negligible d(p)/d(f)) becoming important above ca. d(p) = 100 nm. We conclude from these data that the effective interception diameter, d(p,icpt,eff), of the particles studied is systematically larger than their stated mobility diameters-a situation which will deserve further attention in future studies. Encouraged by these preliminary but instructive comparisons, we expect that, for many current and future design purposes, our present class of semi-analytic/nonstochastic/multi-mechanism methods will provide a welcome complement, if not alternative, to much more computationally-intensive simulation methods for realistic fibrous media that have been described and implemented in the recent aerosol filtration literature. The consequences of including these structural features of fibrous filters in the presence of aerosol size-and shape polydispersity will be the subject of future studies, based on the generalized Population Balance Equation developed/proposed in Section 3.3.

    An innovative method for soot deposit quantification using a CO2 sensor: Application to fire studies in research facilities

    Kort, A.Ouf, F. -x.Lakhmi, R.Gelain, T....
    11页
    查看更多>>摘要:In industrial facilities handling or manufacturing hazardous materials, fires are one of the major hazards. Therefore, it is important to have tools to better understand the transport and deposition phenomenon of emitted particles in order to take into account their consequences on safety devices. For this purpose and due to the lack of quantitative soot deposition data under realistic fire conditions, an innovative method for soot quantification in experimental facilities devoted to fire research has been developed. This method is based on the quantification of gases emitted during regeneration of a resistive sensor surface and has a higher detection limit than the electrical conductance quantification method previously proposed and validated by (Kort et al., 2021). A proof of feasibility has been shown for two types of soot and a prediction curve has been proposed for deposited masses which vary between 16 and 350 mu g (1304 mg m- 2 and 28,525 mg m- 2). The applicability of this measurement method to realistic industrial fire situation is finally verified taking into account the mean deposition mass per surface area observed in this context.