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Химия природных соединений
Редакция журнала 'Химия природных соединений'
Химия природных соединений

Редакция журнала 'Химия природных соединений'

0023-1150

Химия природных соединений/Journal Химия природных соединений
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    GLYCEROGLYCOLIPIDS AND DIPEPTIDE DERIVATIVES FROM THE BROWN ALGA Sargassum naozhouense

    Wenhao CaoYan PengTao Yan
    2页
    查看更多>>摘要:The seaweed Sargassum naozhouense C.K.Tseng & Lu Baoren(Sargassaceae)is an edible brown alga that belongs to the genus Sargassum(1).It has a number of pharmaceutical functions in Chinese folk such as treating infections,laryngitis,and other ailment(2).Our previous study reported the isolation and identification of seven norisoprenoids,ten steroids,and one new amide derivative from б",naozhouense(3-5).Here,in this continuing study on the chemical constituents of S,naozhouense,five glyceroglycolipids and two dipeptide derivatives,along with three other compounds,were obtained.All compounds were isolated for the first time from naozhouense.

    COMPOSITION OF SELECTED LIPID FRACTIONS IN 13 ALPINE CRYOPHYTIC PLANT SPECIES GROWING IN THE EASTERN PAMIR MOUNTAINS,TAJIKISTAN

    Monika MetrakAgata TrojanMalgonata Suska-Malawska
    4页
    查看更多>>摘要:In high-altitude areas,cryophyte vegetation shapes the ecology of alpine ecosystems.To survive under harsh environmental conditions,these plants employ different physiological and ecological strategies.Among them is the production of diverse lipid compounds,which protect plants against various stresses,including drought,extreme temperatures,UV radiation,and soil salinity.Non-woody aboveground plant organs are covered with a layer of cuticular waxes,containing a complex mixture of long-chain fatty acids,aldehydes,alkanes,akohols,and ketones,which,due to their hydrophobicity,lessen uncontrolled water losses(1,2).In plants exposed to low air temperatures,the content of unsaturated fatty acids increases,which helps to maintain membrane fluidity and chloroplast functioning,thus preventing cold damage(3,4).Lipid secondary plant metabolites(e.g.phenylpropanoids and terpenoids)and neutral lipids(triacylglycerol)play an important role in photoprotection mechanisms,either by effectively absorbing UVA + UVB radiation without promotion of further photochemical reactions or by dissipating excess radiation energy(5,6).Both the maintenance of membrane fluidity under low temperatures and production of photoprotective lipid compounds are plastic responses to variability of climatic factors.Contrastingly,qualitative and quantitative composition of cuticular waxes seems to be more fixed and driven by genetic differences between species and populations rather than short-term climatic variability(7).

    CHEMICAL CONSTITUENTS OF THE PROCESSED ROOTS OF Brassica rapa

    Guang-Da LiHong-Mei ZhaoRao-Ji PingPuo
    2页
    查看更多>>摘要:Brassica rapa L.,belonging to Cruciferae,is a traditional Chinese medicine that is used to treat cough,indugestion,and so on(1).Previous investigation revealed the constituents of Brassica rapa L.,including polysaccharides,flavones,saponin,and volatile components(2,3); some of the secondary metabolites and extracts exhibited antioxidant(1,2),antihypoxia(3,4),antitumor(5),hypolipidemic(6),and immune enhancement activity(7).

    ЛИПИДЫ ХЛОРОФОРМНОГО ЭКСТРАКТА НАДЗЕМНОЙ ЧАСТИ Astragalus villosissimus

    Н.К.ЮлдашеваШ.К.ХидоятоваС.Д.Русакова
    2页
    查看更多>>摘要:Astragalus villosissimus Bunge(астрагал косматейший,семейство Fabaceae)-многолетний,эфемероидный кустарник высотой до 1 м,произрастающий на гипсовых,серо-коричневых,песчаных почвах,продолжительность жизни до 12 лет(1),эндемичное растение южных пустынь Центральной Азии(2).Для растения характерно раннее опадание листьев,отмирание молодых ветвей,стремительное цветение и быстрое созревание плодов перед жарким летом.Цветки собраны в большое соцветие,рыхлую кисть или колос(около 1 см),венчик пурпурно-красный или желтовато-белый.Вегетативный рост проходит с марта по апрель.Этот вид астрагала охотно поедают верблюды и овцы(1,2).

    SECONDARY METABOLITES FROM THE FRUITING BODIES OF Coriolopsis aspera IN VIETNAM AND THEIR BIOACTIVITIES

    Nguyen Ngoc ThuanNguyen Thi NganPing-Chung Kuo
    3页
    查看更多>>摘要:Coriolopsis is a genus of fungi in the family Polyporaceae.Most of them are distributed in tropical and subtropical Asia.Although the component of the fruiting bodies of Coriolopsis has been reported(1-5),there are few studies concerning the secondary metabolites produced by fungi of the genus Coriolopsis.Today,Coriolopsis is also broadly used as traditional medicines in India,China,and Japan as antioxidant,antitumor,antiviral,antimicrobial,immunomodulatory agents,etc.(6-8).They also contain various bioactive molecules,including terpenoids,steroids,phenols,nucleotides,glycoprotein derivatives,and polysaccharides(1-5).They are also suggested as promising sources for screening new natural products.In our continuing program to search for new metabolites from the natural medicinal fungi C.aspera,herein we report the characterization of nine compounds(1-9)isolated from the fruiting bodies of С aspera for the first time.

    BIOACTIVE CHEMICAL CONSTITUENTS OF Leucas zeylanica

    Xue-MingJiling GuangyingNajat Nidhal
    3页
    查看更多>>摘要:Leucas zeylanica(L.)W.T.Aiton is a plant species belonging to the genus Leucas(Lamiaceae).Its leaves yare used as a vegetable and in many traditional herbal remedies to treat infections,gout,skin illnesses,and related disorders.It is also used as an agricultural insecticide because of its aromatic,stomachic,and carminative properties(1).L zeylanica displays a broad spectrum of biological activities,such as antibacterial,anti-inflammatory,anthelmintic,antifungal,and mosquito larvicidal activities(2-6).

    SECONDARY METABOLITES FROM STEM BARKS OF Catalpa bungei

    Yeye HuWei LiuHuayu Liu
    3页
    查看更多>>摘要:Catalpa bungei C.A.Mey.(Bignoniaceae),a deciduous arbor species,is indigenous to western and middle regions of China,С bungei is an ancient ornamental woody plant widely used in landscaping.Wood of С bungei shows excellent mechanical performance and superior durability that can resist the corrosion caused by microorganisms and insects(1,2).Extracts of С bungei plant materials have long been used in Chinese folk remedies for treating,preventing,or alleviating various disorders or diseases,such as edema,nephritis,eczema,leprosy,cystitis,and gastric cancer(3).The literature indicates that С bungei leaves and seed oil show significant antioxidant and antitumor activities(2-4).Previous phytochemical study of seeds and leaves of С bungei led to the isolation of several classes of chemical constituents,including iridoids,triterpenoids,lignans,phenylethanoid,and flavonoids glycosides(3-6).However,screening of the secondary metabolites of the barks of this tree species has not been carried out to date.In this phytochemical investigation of С bungei,eight secondary metabolites were isolated from its stem barks,and their chemical structures were characterized as salirepin 7-O-benzoate(1),oleanolic acid(2),ursolic acid(3),luteolin(4),(+)-catechin(5),luteolin 7-O-β-D-glucopyranoside(6),quercetin 3-O-β-D-xylopyranoside(7),and quercetin 3-O-β-Z)-xylopyranosyI(1→2)-0-β-D-glucopyranoside(8)from their spectroscopic data,including NMR and MS,and by comparison of their spectroscopic data with literature values.It is worth noting that compounds 2,and 5-8 were identified in С bungei for the first time,while compounds 1,2,and 6-8 have never been isolated from the genus Catalpa previously.

    CHEMICAL CONSTITUENTS OF Polyalthia rumphii

    Natasa Mohd ShakriWan Mohd Nuzul Hakimi Wan SallehShamsul Khamis
    2页
    查看更多>>摘要:Polyalthia is one of the largest genera in the Annonaceae family and has been widely used in folk medicine for the treatment of rheumatic fever,gastrointestinal uker,and generalized body pain(1).Polyalthia mmphii(Blume ex Hensch.)Mern is locally known as'merpadi,'and is used in some places in Indonesia to treat skin disease(2).We have recently reported on the chemical compositions of the essential oil from this species(3).As part of our continuing search to explore natural compounds from Polyalthia species,we have investigated the phytochemical study of the leaves of P.mmphii.Fractionation and purification of the extracts afforded four flavones:5,7-dimethoxyflavone(1),4',5,7-trimethoxyflavone(2),5-hydroxy-7-methoxyflavone(3),4'-hydroxy-5,7-dimethoxyflavone(4),together with lupeol(5),taraxerol(6),and β-sitosterol(7).Their structures were established on the basis of spectroscopic analysis and chemical evidence.To the best of our knowledge,all the compounds were isolated for the first time from this species.

    TMETABOLITES FROM THE ACTINOBACTERIUM Saccharomonospora piscinae ISOLATED FROM A FISHPOND SEDIMENT

    Ming-Jen ChengMing-Der WuChung-Yi Chen
    3页
    查看更多>>摘要:Actinobacteria are widely distributed in nature and are very useful in the pharmaceutical industry due to their seemingly unlimited capacity to produce secondary metabolites with diverse chemical structures and biological activities(1-3).They are gram positive,free-living saprophytic bacteria that are found widely distributed in soil,water,and colonizing plants.Actinobacteria inhabitants have been identified as one of the major groups of soil population(2,3),which may vary with the soil type.In the process of investigation of the diversity of cultivable actinobacteria associated with soil from Taiwan,we isolated a strain named 06168H-1~T from a fishpond sediment sample collected from the southern area of Taiwan with a unique morphology(4).This strain was determined to be Saccharomonospora piscinae(Erythrobacteraceae)based on their phenotypic and genotypic data(4).The Promicromonosporaceae(Sphingomonadales,Actinobacteria)constitutes a large family of bacteria.In order to find new bioactive compounds,the rare genera in this group have been identified and studied,including the genus Saccharomonospora piscinae,a genus of bacteria that was only discovered by Nonomura and Ohara(4); currently there are 12 species(4).Saccharomonospora strains are widely distributed in nature,including soil,compost,plant bodies,marine sediments,sponges,and other environments.Therefore,in addition to mesophilic bacteria,there are also thermophilic strains.The spores of some thermophilic strains(Saccharomonospora viridis)can cause allergic pneumonia(farmer's lung disease).In addition,research reports indicate that strains of this genus can decompose many natural or synthetic compounds,such as polyester,rice straw,mushroom compost,food waste compost,protein,and starch.S,piscinae is isolated from the bottom of the southern fish pond.The colony is blue and belongs to aerobic growth.The aerial hyphae will produce non-moving short spore chains.It has high salt tolerance and is a salt-tolerant strain.

    FLAVONOIDS OF Moms alba

    С M LiuH.С YehН.М.Wu
    3页
    查看更多>>摘要:The mulberry tree(Moms alba L.)is a species of Moms belonging to the Moracea family.The trees grow in Europe,West China,Korea,and Japan on a very large scale.Their leaves are very commonly utilized as feed of silkworms.The leaves of Moms plants can also be used as hypoglycemic,hypotensive,diuretic,and antimutagenic tonics(1).As a traditional Chinese medicine,mulberry leaves have been used to treat fever,protect the liver,and lower blood pressure for a long time(2).Previous studies have shown that mulberry leaves exhibit a variety of biological functions,including anti-obesity(3),antidiabetes(4),anti-oxidation(5),anti-inflammation(6),and anti-atherosclerosis(7).To date,a large number of flavones,benzofurans,and alkaloids have been isolated from mulberry leaves(8,9),but the chemical constituents of mulberry leaves and their bioactivities deserve to be further investigated.The MeOH extract of mulberry stems was subjected to solvent partitioning and chromatographic separation to afford eight pure flavonoids.The chemical constituents of mulberry stems were separated by column chromatography.Eight flavonoids,including,5,3'-dihydroxy-7,4'-dimethoxyflavone(1)(10),5-hydroxy-7,8,3',4'-tetramethoxyflavone(2)(11),5,8-dihydroxy-7,3',4'-trimethoxyflavone(3)(12),5,8-dihydroxy-7,4'-dimethoxyflavone(4)(13),5-hydroxy-7,3',4'-trimethoxyflavone(5)(14),3,5-dihydroxy-7,3',4',5'-tetramethoxyflavone(6)(15),5,4'-dihydroxy-7-methoxyflavone(7)(16),and 5,4'-dihydroxy-6,7-dimethoxyflavone(crisimaritin)(8)(17),were isolated from the stems of Moms alba.All of these compounds(1-8)were obtained for the first time from this plant and identified by direct comparison with authentic samples and literature(10-17).