查看更多>>摘要:By a News Reporter-Staff News Editor at Robotics & Machine Learning Daily News Daily News – New research on Autoimmune Diseases an d Conditions - Multiple Sclerosis is the subject of a report. According to news reporting from Madrid, Spain, by NewsRx journalists, research stated, “The Europ ean Cross-Cultural Neuropsychological Test Battery (CNTB) has been proposed as a comprehensive battery for cognitive assessment, reducing the potential impact o f cultural variables. In this validation study, we aimed to evaluate the diagnos tic capacity of CNTB for the assessment of participants with multiple sclerosis (pwMS) compared to the Neuronorma battery (NN) according to the International Cl assification of Cognitive Disorders in MS criteria, and to develop machine learn ing (ML) algorithms to improve the diagnostic capacity of CNTB and to select the most relevant tests.” The news correspondents obtained a quote from the research from Complutense Univ ersity, “Sixty pwMS and 60 healthy controls (HC) with no differences in sex, age , or years of education were enrolled. All participants completed the CNTB and p wMS were also examined with NN, depression, and fatigue scales. Impaired domains and cognitive phenotypes were defined following ICCoDiMS based on CNTB scores a nd compared to NN, according to -1SD and -1.5SD cutoff scores. To select the mos t relevant tests, random forest (RF) was performed for different binary classifi cations. PwMS showed a lower performance compared to HC with medium-large effect sizes, in episodic memory, executive function, attention, and processing speed, in accordance with their characteristic cognitive profile. There were no differ ences in impaired domains or cognitive phenotypes between CNTB and NN, highlight ing the role of episodic memory, executive function, attention, and processing s peed tests. The most relevant tests identified by RF were consistent with inter- group comparisons and allowed a better classification than SD cutoff scores. CNT B is a valid test for cognitive diagnosis in pwMS, including key tests for the m ost frequently impaired cognitive domains in MS.”