首页期刊导航|动物学研究
期刊信息/Journal information
动物学研究
中国科学院昆明动物研究所 中国动物学会
动物学研究

中国科学院昆明动物研究所 中国动物学会

姚永刚

双月刊

0254-5853

zoores@mail.kiz.ac.cn

0871-65199026

650223

昆明市教场东路32号中国科学院昆明动物研究所

动物学研究/Journal Zoological ResearchCSCD北大核心CSTPCDSCI
查看更多>>本刊创刊于1980年。是中国科学院昆明动物研究所主办的向国内外公开发行的学报级学术性期刊。以报道我国动物学领域的新成果、新进展为已任。在《中文核心期刊要目总览》中多次被列为动物学类核心期刊。本刊辟有研究论文、综述、简报、通讯、书评等栏目，主要刊登动物学领域各分支学科有创新性的基础和应用基础研究报告；结合本人研究工作，反映国际最新研究水平的综述；研究简报、快报；新书评介等。近年发表论文中，动物生态医学、进化生物学分别占30%以上。本刊读者对象为科研机构、大专院校从事动物学研究、教学以及资源环境保护与管理的有关人员；也可为从事生命科学、医学、农林牧渔等方面的科研、教学和生产管理人员提供参考资料。
正式出版
收录年代

    ZR and ZRDC embrace a new era

    Yong-Gang YaoYong-Tang Zheng
    1-2页
      原文链接:
    • 万方数据
    • 维普

    A wide hybrid zone mediated by precipitation contributed to confused geographical structure of Scutiger boulengeri

    Xiu-Qin LinYin-Meng HouWei-Zhao YangSheng-Chao Shi...
    3-19页
    查看更多>>摘要：Confused geographical structure of a population and mitonuclear discordance are shaped by a combination of rapid changes in population demographics and shifts in ecology.In this study,we generated a time-calibrated phylogeny of Scutiger boulengeri,an endemic Xizang alpine toad occurring in mountain streams on the Qinghai-Xizang(Tibet)Plateau(QTP).Based on three mitochondrial DNA(mtDNA)genes,eight clades were assigned to three deeply divergent lineages.Analysis of nuclear DNA(nuDNA)genes revealed three distinct clusters without geographic structure,indicating significantly high rates of gene flow.Coalescent theory framework analysis(approximate Bayesian computation model DIYABC and Migrate-N)suggested that divergence of the main intraspecific clusters was the result of hybridization after secondary contact in the Holocene around 0.59 million years ago(Ma).The ratio of mtDNA FST(fixation index)to nuDNA FST was 2.3,thus failing to show male-biased dispersal.Geographic cline analysis showed that a wide hybrid zone was initially established in southwestern China,without significant reproductive isolation but with strong introgression in S.boulengeri,suggesting high hybrid fitness.Furthermore,mtDNA genes exhibited isolation by distance(IBD)while nuDNA genes exhibited significant isolation by environment(IBE).Results suggested that mitonuclear discordance may have initially been caused by geographic isolation,followed by precipitation-mediated hybridization,producing a wide hybrid zone and geographic structure confusion of nuDNA genes in S.boulengeri.This study indicated that complicated historical processes may have led to specific genetic patterns,with a specific climate factor facilitating gene flow in the system.
      原文链接:
    • 万方数据
    • 维普

    Genomic analysis of indigenous goats in Southwest Asia reveals evidence of ancient adaptive introgression related to desert climate

    Hojjat Asadollahpour NanaeiYudong CaiAkil AlshawiJiayue Wen...
    20-29页
    查看更多>>摘要：Understanding how evolutionary pressures related to climate change have shaped the current genetic background of domestic animals is a fundamental pursuit of biology.Here,we generated whole-genome sequencing data from native goat populations in Iraq and Pakistan.Combined with previously published data on modern,ancient(Late Neolithic to Medieval periods),and wild Capra species worldwide,we explored the genetic population structure,ancestry components,and signatures of natural positive selection in native goat populations in Southwest Asia(SWA).Results revealed that the genetic structure of SWA goats was deeply influenced by gene flow from the eastern Mediterranean during the Chalcolithic period,which may reflect adaptation to gradual warming and aridity in the region.Furthermore,comparative genomic analysis revealed adaptive introgression of the KITLG locus from the Nubian ibex(C.nubiana)into African and SWA goats.The frequency of the selected allele at this locus was significantly higher among goat populations located near northeastern Africa.These results provide new insights into the genetic composition and history of goat populations in the SWA region.
      原文链接:
    • 万方数据
    • 维普

    Delineation of biomarkers and molecular pathways of residual effects of fluoxetine treatment in juvenile rhesus monkeys by proteomic profiling

    Yu YanDong Ik ParkAnja HornMari Golub...
    30-42页
    查看更多>>摘要：Fluoxetine(Prozac™)is the only antidepressant approved by the US Food and Drug Administration(FDA)for the treatment of major depressive disorder(MDD)in children.Despite its considerable efficacy as a selective serotonin reuptake inhibitor,the possible long-term effects of fluoxetine on brain development in children are poorly understood.In the current study,we aimed to delineate molecular mechanisms and protein biomarkers in the brains of juvenile rhesus macaques(Macaca mulatta)one year after the discontinuation of fluoxetine treatment using proteomic and phosphoproteomic profiling.We identified several differences in protein expression and phosphorylation in the dorsolateral prefrontal cortex(DLPFC)and cingulate cortex(CC)that correlated with impulsivity in animals,suggesting that the GABAergic synapse pathway may be affected by fluoxetine treatment.Biomarkers in combination with the identified pathways contribute to a better understanding of the mechanisms underlying the chronic effects of fluoxetine after discontinuation in children.
      原文链接:
    • 万方数据
    • 维普

    EcR/USP-1-mediated ecdysteroid signaling regulates wolf spider(Pardosa pseudoannulata)development and reproduction

    Zhi-Ming YangYang-Yang YanYong WuNa Yu...
    43-52页
    查看更多>>摘要：Lycosidae females demonstrate meticulous maternal care of offspring by carrying egg sacs and juvenile spiderlings during the reproductive stage.Nuclear receptors(NRs),especially the ecdysone receptor(EcR)and ultraspiracle(USP),have attracted considerable attention in the regulation of arthropod development and reproduction due to their pivotal roles in ecdysteroid signaling cascades.In the present study,23 NRs,including one EcR and two USPs,were identified in the genome of the predatory wolf spider Pardosa pseudoannulata.RNA interference(RNAi)targeting EcR and USP-1 inhibited spiderling development and resulted in non-viable eggs in the egg sacs.EcR and USP-1 responded to changes in ecdysteroid levels,and interference in ecdysteroid biosynthesis led to similar phenotypes as dsEcR and dsUSP-1 treatments.These findings suggest that EcR/USP-1-mediated ecdysteroid signaling regulates P.pseudoannulata development and reproduction.The P.pseudoannulata females with suppressed ecdysteroid signaling proactively consumed their non-viable egg sacs,resulting in a 7.19 d shorter first reproductive cycle than the controls.Termination of the failed reproductive cycle enabled the spiders to produce a new egg sac more rapidly.This reproductive strategy may partially rescue the reduction in population growth due to non-viable eggs and compensate for the physiological expenditure of wasted maternal care,which would be beneficial for the conservation of P.pseudoannulata populations and their natural control of insect pests.
      原文链接:
    • 万方数据

    Chicken chromatin accessibility atlas accelerates epigenetic annotation of birds and gene fine-mapping associated with growth traits

    Xiao-Ning ZhuYu-Zhe WangChong LiHan-Yu Wu...
    53-62页
    查看更多>>摘要：The development of epigenetic maps,such as the ENCODE project in humans,provides resources for gene regulation studies and a reference for research of disease-related regulatory elements.However,epigenetic information,such as a bird-specific chromatin accessibility atlas,is currently lacking for the thousands of bird species currently described.The major genomic difference between birds and mammals is their shorter introns and intergenic distances,which seriously hinders the use of humans and mice as a reference for studying the function of important regulatory regions in birds.In this study,using chicken as a model bird species,we systematically compiled a chicken chromatin accessibility atlas using 53 Assay of Transposase Accessible Chromatin sequencing(ATAC-seq)samples across 11 tissues.An average of 50 796 open chromatin regions were identified per sample,cumulatively accounting for 20.36%of the chicken genome.Tissue specificity was largely reflected by differences in intergenic and intronic peaks,with specific functional regulation achieved by two mechanisms:recruitment of several sequence-specific transcription factors and direct regulation of adjacent functional genes.By integrating data from genome-wide association studies,our results suggest that chicken body weight is driven by different regulatory variants active in growth-relevant tissues.We propose CAB39L(active in the duodenum),RCBTB1(muscle and liver),and novel long non-coding RNA ENSGALG00000053256(bone)as candidate genes regulating chicken body weight.Overall,this study demonstrates the value of epigenetic data in fine-mapping functional variants and provides a compendium of resources for further research on the epigenetics and evolution of birds and mammals.
      原文链接:
    • 万方数据
    • 维普

    Depletion of stearoyl-CoA desaturase(scd)leads to fatty liver disease and defective mating behavior in zebrafish

    Shan-Shan XuYi LiHou-Peng WangWen-Bo Chen...
    63-77页
    查看更多>>摘要：Stearyl coenzyme A desaturase(SCD),also known as delta-9 desaturase,catalyzes the rate-limiting step in the formation of monounsaturated fatty acids.In mammals,depletion or inhibition of SCD activity generally leads to a decrease in triglycerides and cholesteryl esters.However,the endogenous role of scd in teleost fish remains unknown.Here,we generated a zebrafish scd mutant(scd-/-)to elucidate the role of scd in lipid metabolism and sexual development.Gas chromatography-mass spectrometry(GC-MS)showed that the scd-/-mutants had increased levels of saturated fatty acids C16:0 and C18:0,and decreased levels of monounsaturated fatty acids C16:1 and C18:1.The mutant fish displayed a short stature and an enlarged abdomen during development.Unlike Scd-/-mammals,the scd-/-zebrafish showed significantly increased fat accumulation in the whole body,especially in the liver,leading to hepatic mitochondrial dysfunction and severe cell apoptosis.Mechanistically,srebf1,a gene encoding a transcriptional activator related to adipogenesis,acc1 and acaca,genes involved in fatty acid synthesis,and dgat2,a key gene involved in triglyceride synthesis,were significantly upregulated in mutant livers to activate fatty acid biosynthesis and adipogenesis.The scd-/-males exhibited defective natural mating behavior due to defective genital papillae but possessed functional mature sperm.All defects in the scd-/-mutants could be rescued by ubiquitous transgenic overexpression of scd.In conclusion,our study demonstrates that scd is indispensable for maintaining lipid homeostasis and development of secondary sexual characteristics in zebrafish.
      原文链接:
    • 万方数据

    Whole-genome resequencing reveals recent signatures of selection in five populations of largemouth bass(Micropterus salmoides)

    Cheng-Fei SunXin-Hui ZhangJun-Jian DongXin-Xin You...
    78-89页
    查看更多>>摘要：Largemouth bass(Micropterus salmoides)isan economically important fish species in North America,Europe,and China.Various genetic improvement programs and domestication processes have modified its genome sequence through selective pressure,leaving nucleotide signals that can be detected at the genomic level.In this study,we sequenced 149 largemouth bass fish,including protospecies(imported from the US)and improved breeds(four domestic breeding populations from China).We detected genomic regions harboring certain genes associated with improved traits,which may be useful molecular markers for practical domestication,breeding,and selection.Subsequent analyses of genetic diversity and population structure revealed that the improved breeds have undergone more rigorous genetic changes.Through selective signal analysis,we identified hundreds of putative selective sweep regions in each largemouth bass line.Interestingly,we predicted 103 putative candidate genes potentially subjected to selection,including several associated with growth(psst1 and grb10),early development(klf9,sp4,and sp8),and immune traits(pkn2,sept2,bcl6,and ripk2).These candidate genes represent potential genomic landmarks that could be used to improve important traits of biological and commercial interest.In summary,this study provides a genome-wide map of genetic variations and selection footprints in largemouth bass,which may benefit genetic studies and accelerate genetic improvement of this economically important fish.
      原文链接:
    • 万方数据
    • 维普

    Global freshwater assessment of establishment risk of invasive Alligator gar(Atractosteus spatula)and risks to freshwater ecosystems in China

    Wen-Dong XieZhi-Xin WenKai SongBao-Cheng Guo...
    90-93页
      原文链接:
    • 万方数据

    Generation of a tree shrew breast cancer model using lentivirus expressing PIK3CA-H1047R

    Li ZengHong-Yan ZhangChuan-Yu YangZhuo Cheng...
    94-97页
      原文链接:
    • 万方数据
    • 维普