Tianshi WangGijs van SoestAntonius F.W.van der Steen
15-17页
查看更多>>摘要:We have developed a new form of intravascular optical coherence tomography (IV-OCT) that allows the extremely fast acquisition of high-resolution images of the coronary arteries.This process leads to much better image quality by eliminating cardiac motion artefacts and undersampling.It relies on a catheter that incorporates a synchronous micromotor with a diameter of 1.0 mm and a rotational speed of up to 5600 revolutions per second, enabling an IV-OCT frame rate of 5.6 kHz.This speed is matched by a wavelength-swept laser that generates up to 2.8 million image lines per second.With this setup, our team achieved IV-OCT imaging of up to 5600 frames per second (fps) in vitro and 4000 fps in vivo, deployed at a 100 mm·s-1 pullback velocity.The imaging session is triggered by the electrocardiogram of the subject, and can scan a coronary artery in the phase of the heartbeat where the heart is at rest, providing a name for this new technology: the "Heartbeat OCT."
查看更多>>摘要:Magnetic helical micro-and nanorobots can perform 3D navigation in various liquids with a sub-micrometer precision under low-strength rotating magnetic fields (< 10 mT).Since magnetic fields with low strengths are harmless to cells and tissues, magnetic helical micro/nanorobots are promising tools for biomedical applications, such as minimally invasive surgery, cell manipulation and analysis, and targeted therapy.This review provides general information on magnetic helical micro/nanorobots, including their fabrication, motion control, and further functionalization for biomedical applications.