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中国化学快报（英文版）
中国化学快报（英文版）

梁晓天

月刊

1001-8417

cclbj@imm.ac.cn

010-63165638

100050

北京市先农坛街1号

中国化学快报（英文版）/Journal Chinese Chemical LettersCSCDCSTPCD北大核心SCI
查看更多>>本刊是由中国科协主管、中国化学会主办、中国医学科学院药物所承办的学术期刊，是由著名化学家梁晓天院士主编。是中国化学界通向世界的窗口，内容覆盖化学全领域。本刊的办刊宗旨是“新、快、准”，我们将坚持这个宗旨，力求及时反映化学研究中各个相关领域内的最新进展及热点问题，主要读者群是科研人员、研究生、大学教师。现已被国内外多家数据库收录，如SCI　Search、Chemical Abstract、Research Alert、Chemistry Citation Index、《日本科技文献速报》、万方数据数字化期刊群、中国学术期刊过刊全文数据库、中国学术期刊（光盘版）、中国学术期刊文摘、中文期刊全文数据库、俄罗斯Рж期刊源等。
正式出版
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    Sustainable electrosynthesis:Enantioselective electrochemical Rh(Ⅲ)/chiral carboxylic acid-catalyzed oxidative C-H cyclization coupled with hydrogen evolution reaction

    Xinghui YaoZhouyu WangDa-Gang Yu
    1-3页
      原文链接:
    • 万方数据

    Copper-mediated assembly of SO2F group via radical fluorine-atom transfer strategy

    Yu-Yu TanLin-Heng HeWei-Min He
    4-5页
      原文链接:
    • 万方数据

    Oral delivery of insulin by barbed microneedles actuated by intestinal peristalsis

    Qin YuHaisheng HeJianping QiYi Lu...
    6-8页
      原文链接:
    • 万方数据
    • 维普

    Photochemical reactions as synthetic tool for pharmaceutical industries

    Shehla KhalidMuhammad BilalNasir RasoolMuhammad Imran...
    9-31页
    查看更多>>摘要：In the quest for new agrochemicals and pharmaceuticals,chemists seek access to reliable and mild syn-thetic techniques to allow for the systematic modification of chemical structures,exploration of unex-plored chemical space,and facilitation of practical synthesis in their search for novel agrochemicals and pharmaceuticals.In this regard,photocatalytic reactions enabled the synthesis of intricate and more func-tionalized compounds.This review overviews the developed synthetic methodologies and their utility in the chemical synthesis of pharmaceuticals.This review also offers in-depth insights into contemporary photoredox reactions such as allylic additions,cyclization,reductive cross-coupling,C-H activation,ring opening,oxidative cross-coupling,dehydrogenation,desulphonation,and decarboxylation.It provides a positive outlook for the promising future of this field.
      原文链接:
    • 万方数据
    • 维普

    Recent advances in FeCl3-photocatalyzed organic reactions via hydrogen-atom transfer

    Xiao-Ya YuanCong-Cong WangBing Yu
    32-40页
    查看更多>>摘要：In recent years,FeCl3-photocatalyzed direct C-H/Si-H bond functionalization reactions have attracted huge attention.In those transformations,chlorine radical(Cl·)could be generated from FeCl3 via a ligand-to-metal charge transfer(LMCT)/homolysis process under light irradiation.The resulting chlorine radical subsequently acts as a hydrogen atom transfer(HAT)agent to abstract the hydrogen atom of aliphatic C-H,O-H,or Si-H bonds to give the corresponding C/Si/O-centered radicals for various organic trans-formations.In this review,we summarized the recent advances in the application of FeCl3 as a HAT photocatalyst for the C/Si-H functionalization to construct C-C,C-N,C-Si,C-S,C-B,and C-P bonds.
      原文链接:
    • 万方数据

    The choice of antimicrobial polymers:Hydrophilic or hydrophobic?

    Zixu XiePengfei ZhangZiyao ZhangChen Chen...
    41-53页
    查看更多>>摘要：Owing to the spread of COVID-19,it is difficult to ignore the existence and importance of antimicrobial polymers(AMPs)because most protective appliances are made of polymers.Generally,bacteria prefer hydrophilic compounds,while fungi prefer hydrophobic ones.In recent decades,AMPs have made signif-icant strides due to the versatile design of the functional groups or units for hydrophilic,hydrophobic,or amphiphilic performances.This review summarizes the advances of AMPs itself from the perspective of their wettability.Moreover,this study aims to clarify how the functional groups determine the interaction between the polymer and microorganisms directly affects the antimicrobial efficacy of the designed poly-mers.Based on the advances,the challenges and outlooks of AMPs from the perspective of wettability are systematically discussed to build a bridge between the structural design of AMPs and the requirements of practical applications.
      原文链接:
    • 万方数据
    • 维普

    PEDOT-based thermoelectric composites:Preparation,mechanism and applications

    Jia FuShilong ZhangLirong LiangChunyu Du...
    54-64页
    查看更多>>摘要：Thermoelectric(TE)materials enable effective and direct energy conversions between heat and elec-tricity,displaying wide applications including waste/low-grade heat harvesting,local cooling,sensing and wearable electronics.Among the recently-developed organic and composite TE materials,poly(3,4-ethylenedioxythiophene)(PEDOT)is perhaps the most successful and frequently reported type.Herein,we aim to review the recent advances of the synthesis,mechanism and applications of PEDOT-based TE composites.First,the research background and the history of TE materials are briefly introduced.Next,the synthesis and TE performance of PEDOT-based composites are summarized according to the sequence of films,hydrogels/aerogels and fibers/yarns.Then,the mechanism,structure and property are elucidated.After that,the recent development and its applications of power generation and sensing are highlighted.Finally,we provide an outlook on the prospects and the challenges of PEDOT-based TE com-posites.
      原文链接:
    • 万方数据
    • 维普

    Exosome-biomimetic nanocarriers for oral drug delivery

    Fengjie LiuFansu MengZhenjiang YangHuan Wang...
    65-71页
    查看更多>>摘要：Exosomes as authigenous nanovesicles secreted by living cells represent a significant class of biomaterials.By virtue of their unique roles in intercellular communication,exosomes can mediate intercellular infor-mation/cargoes exchange as messenger and facilitate drug delivery as smart vehicles.Oral medication is the most clinically relied upon route of administration and can achieve both topical and systemic ther-apeutic effects after absorption.Exosomes and exosome-derived vectors have shown to be of high value in oral drug delivery,since they enable efficient oral delivery of therapeutic molecules by targeting in-testinal epithelial cells.In recent years,exosome-biomimetic nanocarriers have emerged as an important catalyzer in innovating oral drug delivery systems.In this work,we roundly reviewed the biogenesis and functions of exosomes,their extraction and characterization methods,resources available for exosomes harvest,and design philosophy of exosome-derived vehicles,particularly highlighting the oral delivery application of exosome-biomimetic nanocarriers for diverse medicines.Accumulating evidence suggests that exosome-biomimetic nanocarriers hold great promise for oral delivery of intractable drugs with po-tential biopharmaceutic issues.
      原文链接:
    • 万方数据
    • 维普

    Research advances of nanoparticles for CAR-T therapy in solid tumors

    Bohan ChenLiming GongJing FengMingji Jin...
    72-82页
    查看更多>>摘要：As one of the most promising adoptive T-cell therapies,chimeric antigen receptor T-cell(CAR-T)therapy has acquired Food and Drug Administration(FDA)approval for a variety of products and has been used successfully in the treatment of malignant hematological tumors.CAR-T therapy,on the other hand,faces a number of obstacles in the field of solid tumor therapy that limit its widespread clinical implemen-tation.Significant advances in nanoparticle research in cancer therapy and immunotherapy have been made in recent years,providing novel strategies to address the challenges encountered by CAR-T therapy in the treatment of solid tumors.This review commences with a comprehensive explanation of the basic framework of CAR-T therapy as well as the challenges it faces in the treatment of solid tumors.Subse-quently,we encapsulate a summary of the developmental research combining nanoparticles with CAR-T cells for the treatment of solid tumors,which includes gene transfection,cell activation and expansion,targeted infiltration,immune escape inhibition,and combination with other therapies.Coupled with the overview of the research progress,a discussion has been initiated on the challenges and perspectives of CAR-T based on nanoparticles.
      原文链接:
    • 万方数据
    • 维普

    Progress and challenge of functional single-atom catalysts for the catalytic oxidation of volatile organic compounds

    Zeyu JiangYadi WangChangwei ChenChi He...
    83-91页
    查看更多>>摘要：The catalytic oxidation of volatile organic compounds(VOCs)is of considerable significance for the sus-tainable development of the chemical industry;thus,considerable efforts have been devoted to the ex-ploration of efficient catalysts for use in this reaction.In this regard,the development and utilization of single-atom catalysts(SACs)in VOCs decomposition is a rapidly expanding research area.SACs can be employed as potential catalysts for oxidizing VOC molecules due to their optimal utilization efficiency,unique atomic bonding structures,and unsaturated orbits.Progress has been achieved,while the chal-lenges surrounding precise regulation of the microstructures of SACs for improving their low-temperature efficiency,stability,and product selectivity under practical conditions are remaining.Therefore,elucidat-ing structure-performance relationships and establishing intrinsic modulating mechanisms are urgently required for guiding researchers on how to synthesize effective and stable functional SACs proactively.Herein,recent advances in the design and synthesis of functional SACs for application in the catalytic oxidation of VOCs are summarized.The experimental and theoretical studies revealing higher efficiency,stability,and selectivity of as-prepared functional SACs are being highlighted.Accordingly,the future per-spectives in terms of promising catalysts with multi-sized composite active sites and the illustration of intrinsic mechanism are proposed.The rapid intelligent screening of applicable SACs and their industrial applications are also discussed.
      原文链接:
    • 万方数据
    • 维普