中国化学快报(英文版)2024,Vol.35Issue(9) :9-31.DOI:10.1016/j.cclet.2024.109498

Photochemical reactions as synthetic tool for pharmaceutical industries

Shehla Khalid Muhammad Bilal Nasir Rasool Muhammad Imran
中国化学快报(英文版)2024,Vol.35Issue(9) :9-31.DOI:10.1016/j.cclet.2024.109498

Photochemical reactions as synthetic tool for pharmaceutical industries

Shehla Khalid 1Muhammad Bilal 2Nasir Rasool 1Muhammad Imran3
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作者信息

  • 1. Department of Chemistry,Government College University,Faisalabad 38000,Pakistan
  • 2. Department of Chemistry,Government College University,Faisalabad 38000,Pakistan;School of Chemistry and Chemical Engineering,Shandong University,Ji'nan 250100,China
  • 3. Department of Chemistry,Faculty of Science,King Khalid University,Abha 61413,Saudi Arabia
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Abstract

In the quest for new agrochemicals and pharmaceuticals,chemists seek access to reliable and mild syn-thetic techniques to allow for the systematic modification of chemical structures,exploration of unex-plored chemical space,and facilitation of practical synthesis in their search for novel agrochemicals and pharmaceuticals.In this regard,photocatalytic reactions enabled the synthesis of intricate and more func-tionalized compounds.This review overviews the developed synthetic methodologies and their utility in the chemical synthesis of pharmaceuticals.This review also offers in-depth insights into contemporary photoredox reactions such as allylic additions,cyclization,reductive cross-coupling,C-H activation,ring opening,oxidative cross-coupling,dehydrogenation,desulphonation,and decarboxylation.It provides a positive outlook for the promising future of this field.

Key words

Photocatalyst/Photochemical reactions/Drugs/Natural products/Late-stage functionalization

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出版年

2024
中国化学快报(英文版)
中国化学会

中国化学快报(英文版)

CSTPCD
影响因子:0.771
ISSN:1001-8417
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