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中国神经再生研究（英文版）
中国康复医学会
中国神经再生研究（英文版）

中国康复医学会

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中国神经再生研究（英文版）/Journal Neural Regeneration ResearchCSCDCSTPCD北大核心SCI
查看更多>>SCI收录杂志！！！ 本刊为英文版杂志，以国际通用语言研究最前沿、最热点的神经再生问题。创刊起点高，评估论文研究成果的学术标准高，对论文语言表述水平的要求高。 刊物宗旨： 2006年创刊，面向国际、立足国际，以办好一本国际神经再生学科界专家公认的专业性学术期刊为工作目标，主要发表神经再生领域基础及应用基础研究方面的学术文章。 出版重点： 2009年本刊重点出版对神经损伤修复过程中原位神经干细胞以及移植的神经干细胞作用机制的研究，出版神经组织工程、神经退行性疾病组织形态学变化以及中医药对神经细胞、神经组织再生过程中生理、病理结构变化影响的相关研究文章。面向国际，立足国际，关注全球范围内具有创新性的抑制、促进或影响神经细胞、神经组织再生结构变化相关机制的研究，关注由此而发生的一系列功能变化及其相互关系。 感兴趣神经解剖学、病理学、生理学、生物化学、药理学、免疫学、发育学等来自多学科、多层面的题材，感兴趣发表以基础实验性研究为主的揭示大脑皮质、海马、松果体、神经胶质细胞、脊髓神经元、周围神经元以及运动和感觉神经损伤与再生的研究原著，对有助于认识神经再生正常和异常机制的临床类文章，如罕见病例报告、调查分析等也可纳入范围。 欢迎文章从理论假设、研究方法、模型制备、影像学技术等多个视角描述神经再生的相关特点，为读者提供该领域最有价值的学科进展信息及其最新的理论观点，增强对神经再生复杂机制、学说和病理发生过程的理解。一般文章2000-4000单词。 非常注重出版时效。投稿15～30天编辑部采用随机盲法抽取国际评审专家审稿，符合采用标准的文章进入修稿程序，力求出版周期120～180天，以保证高质量优秀稿件抢先出版。 收录情况： 科学引文索引（SCI） 2006年被SCI引文库收录8篇 2008年1月至2008年7月被SCI收录文章188篇 美国生物学文献数据库（BIOSIS） 美国《化学文摘》（CA） 荷兰《医学文摘库/医学文摘》（EM） 波兰《哥伯尼索引》（IC） 中国英文版科技期刊数据库(统计源期刊) 中国科学引文数据库（核心期刊） 2007年被CA收录247篇，被EM收录173篇
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    Resting-state brain network remodeling after different nerve reconstruction surgeries:a functional magnetic resonance imaging study in brachial plexus injury rats

    Yunting XiangXiangxin XingXuyun HuaYuwen Zhang...
    1495-1504页
    查看更多>>摘要：Distinct brain remodeling has been found after different nerve reconstruction strategies,including motor representation of the affected limb.However,differences among reconstruction strategies at the brain network level have not been elucidated.This study aimed to explore intra-network changes related to altered peripheral neural pathways after different nerve reconstruction surgeries,including nerve repair,end-to-end nerve transfer,and end-to-side nerve transfer.Sprague-Dawley rats underwent complete left brachial plexus transection and were divided into four equal groups of eight:no nerve repair,grafted nerve repair,phrenic nerve end-to-end transfer,and end-to-side transfer with a graft sutured to the anterior upper trunk.Resting-state brain functional magnetic resonance imaging was obtained 7 months after surgery.The independent component analysis algorithm was utilized to identify group-level network components of interest and extract resting-state functional connectivity values of each voxel within the component.Alterations in intra-network resting-state functional connectivity were compared among the groups.Target muscle reinnervation was assessed by behavioral observation(elbow flexion)and electromyography.The results showed that alterations in the sensorimotor and interoception networks were mostly related to changes in the peripheral neural pathway.Nerve repair was related to enhanced connectivity within the sensorimotor network,while end-to-side nerve transfer might be more beneficial for restoring control over the affected limb by the original motor representation.The thalamic-cortical pathway was enhanced within the interoception network after nerve repair and end-to-end nerve transfer.Brain areas related to cognition and emotion were enhanced after end-to-side nerve transfer.Our study revealed important brain networks related to different nerve reconstructions.These networks may be potential targets for enhancing motor recovery.
      原文链接:
    • 万方数据
    • 维普

    The burden of upper motor neuron involvement is correlated with the bilateral limb involvement interval in patients with amyotrophic lateral sclerosis:a retrospective observational study

    Jieying WuShan YeXiangyi LiuYingsheng Xu...
    1505-1512页
    查看更多>>摘要：Amyotrophic lateral sclerosis is a rare neurodegenerative disease characterized by the involvement of both upper and lower motor neurons.Early bilateral limb involvement significantly affects patients'daily lives and may lead them to be confined to bed.However,the effect of upper and lower motor neuron impairment and other risk factors on bilateral limb involvement is unclear.To address this issue,we retrospectively collected data from 586 amyotrophic lateral sclerosis patients with limb onset diagnosed at Peking University Third Hospital between January 2020 and May 2022.A univariate analysis revealed no significant differences in the time intervals of spread in different directions between individuals with upper motor neuron-dominant amyotrophic lateral sclerosis and those with classic amyotrophic lateral sclerosis.We used causal directed acyclic graphs for risk factor determination and Cox proportional hazards models to investigate the association between the duration of bilateral limb involvement and clinical baseline characteristics in amyotrophic lateral sclerosis patients.Multiple factor analyses revealed that higher upper motor neuron scores(hazard ratio[HR]=1.05,95％confidence interval[CI]=1.01-1.09,P=0.018),onset in the left limb(HR=0.72,95％CI=0.58-0.89,P=0.002),and a horizontal pattern of progression(HR=0.46,95％CI=0.37-0.58,P＜0.001)were risk factors for a shorter interval until bilateral limb involvement.The results demonstrated that a greater degree of upper motor neuron involvement might cause contralateral limb involvement to progress more quickly in limb-onset amyotrophic lateral sclerosis patients.These findings may improve the management of amyotrophic lateral sclerosis patients with limb onset and the prediction of patient prognosis.
      原文链接:
    • 万方数据
    • 维普

    The effects of exercise interventions on brain-derived neurotrophic factor levels in children and adolescents:a meta-analysis

    Xueyun ShaoLongfei HeYangyang Liu
    1513-1520页
    查看更多>>摘要：Brain-derived neurotrophic factor is a crucial neurotrophic factor that plays a significant role in brain health.Although the vast majority of meta-analyses have confirmed that exercise interventions can increase brain-derived neurotrophic factor levels in children and adolescents,the effects of specific types of exercise on brain-derived neurotrophic factor levels are still controversial.To address this issue,we used meta-analytic methods to quantitatively evaluate,analyze,and integrate relevant studies.Our goals were to formulate general conclusions regarding the use of exercise interventions,explore the physiological mechanisms by which exercise improves brain health and cognitive ability in children and adolescents,and provide a reliable foundation for follow-up research.We used the PubMed,Web of Science,Science Direct,Springer,Wiley Online Library,Weipu,Wanfang,and China National Knowledge Infrastructure databases to search for randomized controlled trials examining the influences of exercise interventions on brain-derived neurotrophic factor levels in children and adolescents.The extracted data were analyzed using ReviewManager 5.3.According to the inclusion criteria,we assessed randomized controlled trials in which the samples were mainly children and adolescents,and the outcome indicators were measured before and after the intervention.We excluded animal experiments,studies that lacked a control group,and those that did not report quantitative results.The mean difference(MD;before versus after intervention)was used to evaluate the effect of exercise on brain-derived neurotrophic factor levels in children and adolescents.Overall,531 participants(60 children and 471 adolescents,10.9-16.1 years)were included from 13 randomized controlled trials.Heterogeneity was evaluated using the Q statistic and I2 test provided by ReviewManager software.The meta-analysis showed that there was no heterogeneity among the studies(P=0.67,I2=0.00％).The combined effect of the interventions was significant(MD=2.88,95％CI:1.53-4.22,P＜0.0001),indicating that the brain-derived neurotrophic factor levels of the children and adolescents in the exercise group were significantly higher than those in the control group.In conclusion,different types of exercise interventions significantly increased brain-derived neurotrophic factor levels in children and adolescents.However,because of the small sample size of this meta-analysis,more high-quality research is needed to verify our conclusions.This meta-analysis was registered at PROSPERO(registration ID:CRD42023439408).
      原文链接:
    • 万方数据
    • 维普