查看更多>>摘要：目的 探讨养元通络针灸疗法治疗功能性消化不良患者胃肠动力障碍的临床疗效。 方法 随机对照研究。抽取2022年6月至2023年6月郑州市中医院收治的的功能性消化不良胃肠动力障碍患者102例，按随机数字表法分为对照组和观察组，每组51例。对照组予以枸橼酸莫沙必利分散片治疗，观察组仅采用养元通络针灸疗法，比较两组治疗后临床疗效、中医症状积分、胃肠道功能[包括胃肠道症状积分问卷评分(GIS)、功能性消化不良症状日记(FDSD)评分]、胃排空时间、胃蛋白酶原水平及安全性。 结果 观察组有效率(98.04%，50/51)高于对照组(82.35%，42/51)，P<0.05。治疗后两组患者中医症状积分、GIS、FDSD评分、胃排空时间、胃蛋白酶原水平均明显改善，且观察组改善情况优于对照组(P<0.05)。两组不良反应发生率比较差异未见统计学意义(P>0.05)。 结论 采用养元通络针灸疗法治疗功能性消化不良患者胃肠动力障碍可取得较好的疗效。 Objective To investigate the clinical efficacy of the Yangyuan Tongluo acupuncture and moxibustion therapy in the treatment of gastrointestinal motility disorders in patients with functional dyspepsia. Methods A total of 102 patients with gastrointestinal motility disorders complicated by functional dyspepsia treated in Zhengzhou Traditional Chinese Medicine Hospital from June 2022 to June 2023 were selected for the randomized controlled study. And they were divided into a control group and an observation group by random number table method, with 51 cases in each group. The control group was given mosapride citrate dispersible tablets, while the observation group received only Yangyuan Tongluo acupuncture and moxibustion therapy. The clinical efficacy, traditional Chinese medicine symptom scores, gastrointestinal function assessed by gastrointestinal symptom score (GIS) and functional dyspepsia symptom diary (FDSD) score, gastric emptying time, levels of gastric pepsinogen and safety were compared between the two groups after treatment. Results The clinical effective rate in the observation group (98.04%, 50/51) was significantly higher than that in the control group (82.35%, 42/51), P<0.05. After treatment, both groups showed significant improvements in traditional Chinese medicine symptom score, GIS score, FDSD score, gastric emptying time, and levels of gastric pepsinogen (P<0.05) and the improvement in the observation group was more significant compared with the control group (P<0.05). There was no stically significant difference in the incidence of adverse reactions between the two group (P>0.05). Conclusions Yangyuan Tongluo acupuncture and moxibustion therapy is effective in treating gastrointestinal motility disorders in patients with functional dyspepsia.
查看更多>>摘要：目的 探讨通脑复原汤联合针刺阳陵泉穴治疗缺血性脑卒中的临床效果。 方法 抽取2019年1月至2021年1月于驻马店市中医院接受诊疗的98例缺血性脑卒中患者为研究对象，按照随机数字表法分为对照组和观察组，每组49例。对照组给予常规西药治疗，观察组采用常规西药＋通脑复原汤＋针刺陵泉穴治疗，两组均连续治疗30 d。观察两组治疗前及治疗30 d时中医证候评分、日常生活能力[日常生活能力量表(ADL)]、生化指标[超氧化物歧化酶(SOD)、一氧化氮(NO)、一氧化氮合成酶(NOS)]，并记录两组不良反应情况。 结果 治疗30 d时，两组中医证候评分均低于治疗前，ADL评分及SOD、NO、NOS水平均高于治疗前(P均<0.05)，且观察组中医证候评分低于对照组，ADL评分及SOD、NO、NOS水平高于对照组(P<0.05)。观察组不良反应发生率(8.16%，4/49)与对照组(6.12%，3/49)比较差异未见统计学意义(P>0.05)。 结论 通脑复原汤联合针刺阳陵泉穴可快速缓解缺血性脑卒中患者的临床症状，提升其日常生活能力，改善生化指标水平，且安全性高。 Objective To investigate the clinical effect of Tongnao Fuyuan decoction combined with acupuncture at Yanglingquan point in the treatment of ischemic stroke. Methods Ninety-eight patients with ischemic stroke who received diagnosis and treatment in Zhumadian Traditional Chinese Medicine Hospital from January 2019 to January 2021 were selected as the research subjects. And they were divided into control group and observation group by random number table method, with 49 cases in each group. The control group was treated with conventional western medicine, while the observation group was treated with conventional western medicine, Tongnao Fuyuan decoction and acupuncture at Yanglingquan point. Both groups were treated continuously for 30 days. The traditional Chinese medicine syndrome score, activities of daily living (ADL) and biochemical indexes, including superoxide dismutase (SOD), nitric oxide (NO) and nitric oxide synthase (NOS), were observed between the two groups before treatment and at 30 days of treatment. And the adverse reactions of the two groups were recorded. Results At 30 days of treatment, the traditional Chinese medicine syndrome score of the two groups were lower than those before treatment, while ADL scores and levels of SOD, NO and NOS of the two groups were higher than those before treatment (all P<0.05). In addition, compared with the control group, the observation group had lower traditional Chinese medicine syndrome score, higher ADL score and higher levels of SOD, NO and NOS (P<0.05). There was no significant difference in the incidence of adverse reactions between the observation group (8.16%, 4/49) and the control group (6.12%, 3/49),P>0.05. Conclusions Tongnao Fuyuan decoction combined with acupuncture at Yanglingquan point can quickly alleviate the clinical symptoms of patients with ischemic stroke, improve their ability of daily living and levels of biochemical indexes, with high safety.
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