Objective:To improve the stability of tea polyphenols(TP).Methods:Hollow mesoporous silica(HMSN)was prepared by using the emulsion template method,and TP was loaded into HMSN by organic solvent impregnation to obtain HMSN@TP complexes.The stability of HMSN@TP was investigated in the presence of light,temperature,acid and alkali as well as gases,and the free radical scavenging ability and antimicrobial properties of TP were examined.Results:The content of TP in the prepared HMSN@TP composite was 10.85%.The water dispersion of TP was effectively improved by the encapsulation of HMSN.Compared with free TP,the retention rate of HMSN@TP was increased by 17%after 7 days of storage.Under different light,temperature,acid-base and gas environment,HMSN encapsulation could significantly reduce the degradation rate of TP and improve the oxidation resistance of TP.In addition,the antibacterial results of Escherichia coli showed that the coating of HMSN did not affect the antibacterial properties of TP.Conclusion:HMSN@TP could effectively improve the stability of TP,and its activity could be better maintained in different environments.Therefore,HMSN could be used as a candidate carrier of TP to improve the stability of TP in different processing processes.