首页|非洲猪瘟病毒VP73蛋白的B细胞表位预测

非洲猪瘟病毒VP73蛋白的B细胞表位预测

扫码查看
[目的]预测非洲猪瘟病毒VP73蛋白的B细胞表位.[方法]综合分析二级结构、亲水性、表面可及性与抗原性指数,预测非洲猪瘟病毒VP73蛋白的抗原表位.[结果]推测B细胞表位位于非洲猪瘟病毒VP73蛋白N端的11~18、26~48、73~82、136~150、159~174、181~189、191~210、247~276、279~295、313~323和382~392区段内或上述区段附近.[结论]应用多参数预测非洲猪瘟病毒VP73蛋白的B细胞表位,为今后进一步研究非洲猪瘟病毒VP73蛋白的特征以及表位疫苗的研制奠定了基础.
The Prediction of B Cell Epitopes for VP73 Protein of African Fever Virus
[Objective] The B cell epitopes for VP73 protein of African swine fever virus was predicted. [Method] Based on the analysis of the amino acidsequence and the flexible regions of VP73 protein, the B cell epitopes for VP73 protein of African swine fever virus were predicted by method of Kyte-Doolittle,Emini and Jameson-Wolf. [Resu]t] The B cell epitopes were located at or adjacent to the N-terminal No.11-18,26-48, 73-82, 136-150, 159-174,181-189,191-210,247-276,279-295,313-323 and 382-392. [Conclusion] The multi-parameters analytic method was adopted to predict the B cell epitopesfor VP73 protein of African swine fever virus, which laid solid foundation for further characterizing the protein of VP73 and researching epitope vaccine.

African swine fever virusVP73 proteinB cell epitope

李倩、姚淑霞

展开 >

烟台大学化学生物理工学院,山东烟台,264005

广西大学生命科学与技术学院,广西南宁,530005

非洲猪瘟病毒 VP73蛋白 B细胞表位

2008

安徽农业科学
安徽省农业科学院

安徽农业科学

CSTPCD北大核心
影响因子:0.413
ISSN:0517-6611
年,卷(期):2008.36(18)
  • 6
  • 4