Study on the Extraction Process of Rhein from RADIX ET RHIZOMA RHEI by Uniform Design
[Objective] To discuss the relationship between related factors and rhein content and optimize the extraction process of rhein from RADIX ET RHIZOMA RHEI by uniform design method. [ Method] Taking the content of rhein as index,uniform design with 4 investigated factors including comminution degree,ethanol concentration,solid -liquid ratio,and extraction time was performed to optimize the extraction process of rhein from RADIX ET RHIZOMA RHEI with TS - NS extraction and concentration device. [ Result] The extraction rate of rhein was the highest in extracts when RADIX ET RHIZOMA RHEI powder sieved with 18 meshes was extracted for 0.5 h with 85% ethanol as solvent under solid -liquid ratio of 1: 10. [ Conclusion ] The technology was scientific and reasonable that could provide a scientific basis for optimizing the extraction process of rhein from RADIX ET RHIZOMA RHEI using ethanol as extracting solvent.
RADIX ET RHIZOMA RHEIRheinExtraction processUniform design