Study on Anti-tumor Constituents from Hydrocotyle sibthorpioides
[Objective] To study anti-tumor constituents from Hydrocotyle sibthorpioides.[Method] The constituents were isolated by chromatography and identified by NMR spectroscopic methods.The anti-tumor experiment in vitro,the MTT was used to screen constituents of Hydrocotyle sibthorpioides.[Result] Compounds 1-4 were isolated and identified.Each extracted parts of Hydrocotyle sibthorpioides all have a certain inhibition effect on LA795,the inhibition effect of N-butanol extract in high concentration of 800μg/ml is the strongest,while the inhibition effects of petroleum ether and ethyl acetate extracts are relative weaker.[Conclusion] The 4 compounds all have a certain inhibition effect on the growth of tumor cells.