山楂黄酮提取物降血脂研究
Research on Hypolipidemic Effect of Hawthorn Flavonoids Extract
张明 1陈珍1
作者信息
- 1. 楚雄医药高等专科学校药学系，云南楚雄675005
- 折叠
摘要
[目的]研究山楂黄酮提取物的降血脂作用,为其相关产品开发应用提供依据。[方法]采用渗漉法提取山楂黄酮,对SD大鼠进行试验,待大鼠形成高脂模型后,采用低、中、高剂量灌胃山楂黄酮提取物,30 d后测定大鼠血脂中总胆固醇、甘油三酯、低密度脂蛋白、高密度脂蛋白的变化。[结果]山楂黄酮提取物使各剂量组大鼠血脂中的总胆固醇、低密度脂蛋白含量明显降低,对甘油三脂、高密度脂蛋白有调节作用。[结论]山楂黄酮提取物具有显著的降血脂功效。
Abstract
Objective] The aim was to study the hypolipidemic effect of hawthorn flavonoids extract, to provide basis for development and appli-cation of relevant products. [Method] The hawthorn flavonoids were extracted by percolation method. The SD rats were used for the experiment, waiting for the formation of high blood lipids in rats, the low, middle and high doses of hawthorn flavonoids extract were used to fill rats’ stomach with high blood fat every day, after 30 days, the changes of total cholesterol, triglyceride, low density lipoprotein, high density lipoprotein in blood lipid in rats were determined. [Result] Hawthorn flavonoids significantly reduced total cholesterol and low density lipoprotein in the blood of SD rats, had a regulating function on triglycerides and high density lipoprotein. [ Conclusion] Hawthorn flavonoids extract has significant hypo-lipidemic effect.
关键词
山楂黄酮/降血脂/总胆固醇/甘油三酯/低密度脂蛋白/高密度脂蛋白Key words
Flavonoid of hawthorn/Hypolipidemic effect/Total cholesterol/Triglyceride/Low density lipoprotein/High density lipoprotein引用本文复制引用
出版年
2016
国家科技期刊平台
NSTL
维普
万方数据