摘要
[目的]研究西藏沙棘（ Hippophae thibetana）叶中的化学成分。[方法]通过硅胶柱色谱法、Sephadex LH－20、MCI柱色谱法及半制备HPLC研究西藏沙棘枝叶的化学成分，依据波谱数据鉴定其化合物结构。[结果]试验共得到7种化合物：Δ5，22豆甾醇（1），齐墩果酸（2），3′－甲氧基－槲皮素－3－O－β－D葡萄糖苷（3），3′－甲氧基－槲皮素－3－O－a－L－鼠李糖－（1→2）－β－D－葡萄糖苷（4），表儿茶素（5），对羟基苯甲酸丁酯（6），3，4－二甲氧基－5－羟基－苯酚－1－O－α－D－阿拉伯糖－（1→6）－β－D－葡萄糖苷（7）；其中化合物1、5、6、7为首次从西藏沙棘中分离得到。[结论]研究可为西藏沙棘资源的综合开发利用提供参考。
Abstract
Objective] To study the chemical constituents in leaves of Hippophae thibetana.[ Method] Seven compounds were isolated by sil-ica gel column chromatography, MCI, Sephadex LH-20 column chromatography, and semi-preparative HPLC.[ Result] Their chemical struc-tures were elucidated by spectra data analysis.Seven compounds were obtained and identified as Δ5,22 stigmasterol (1), oleanolic acid (2), 3′-methoxyl-quercetin-3-O-β-D-glucopyranoside (3), 3′-methoxyl-quercetin-3-O-α-L-rhamnose-(1→2)-β-D-glucopyranoside (4), epicate-chin (5), butylparaben (6), 3,4-dimethoxyl-5-hydroxyl-phenol-1-O-α-D-arabinofuranosyl-(1→6)-β-D-glucopyranoside (7).[Conclusion] Compounds 1, 5, 6 and 7 were obtained from H.thibetana for the first time.
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