萝卜叶不同萃取物对乙酰胆碱酯酶抑制活性研究
Study of Inhibitory Activity of Different Extracts from Radish Leaves to Acetylcholinesterase
王乐 1黄明远 1高品一 1刘学贵1
作者信息
- 1. 沈阳化工大学制药与生物工程学院,辽宁沈阳110142
- 折叠
摘要
[目的]研究萝卜叶不同萃取组分对乙酰胆碱酯酶的抑制活性.[方法]通过对萝卜叶水提原液、水提不同萃取组分及萃取后的水相进行乙酰胆碱酯酶抑制活性测试,对萝卜叶抑制乙酰胆碱酯酶能力进行评价.[结果]以石杉碱甲为对照,萝卜叶不同萃取物对乙酰胆碱酯酶的抑制能力从大到小依次为石杉碱甲、二氯甲烷组分、乙酸乙酯组分、石油醚组分、正丁醇组分、水相、萝卜叶水提原液.[结论]萝卜叶具有较好的乙酰胆碱酯酶抑制活性,并呈现一定的浓度依赖性.
Abstract
[Objective] To study inhibitory activity of different extraction fractions from radish leaves to acetylcholinesterase.[Method] The inhibitory activities of different polarities of water extracts from radish leaves to acetylcholinesterase were determined and the ability of radish leaves inhibiting acetylcholinesterase was evaluated.[Result] Using huperzine as the control,the order of inhibiting ability from strong to weak is huperzine,dichloromethane layer,ethyl acetate layer,petroleum ether layer,butanol layer,water-phase,radish leaf extract.[Conclusion] Radish leaves have a good inhibitory activity to acetylcholinesterase and present a concentration-dependent manner.
关键词
不同萃取组分/乙酰胆碱酯酶/抑制活性/萝卜叶水提原液/水相Key words
Different extraction fractions/Acetylcholinesterase/Inhibitory activity/Radish leaf extract/Water-phase引用本文复制引用
出版年
2017
国家科技期刊平台
NSTL
维普
万方数据