金银花精油及其与β-环糊精包合物的制备工艺研究
Study on the Preparation Processes of Honeysuckle Essential Oil and Its Inclusion Compound with β-cyclodextrin
林玉环 1高昆 1况鹏群 1井文华 1王敏敏 1赵玉萍1
作者信息
- 1. 山东省鲁南中药材工程技术研究中心,临沂大学,山东临沂276000
- 折叠
摘要
[目的]优选金银花精油及其与β-环糊精包合物的制备工艺.[方法]采用水蒸气蒸馏法制备金银花精油,用GC-MS分析金银花精油的主体呈香成分及含量;采用饱和水溶液法,通过正交试验设计,以金银花精油的包合率为指标,考察金银花精油与β-环糊精的包合比例、包合温度、搅拌时间和烘干温度对金银花精油-β-环糊精包合物制备工艺的影响.[结果]水蒸气蒸馏法制备金银花精油的得率为0.12％,经GC-MS分析,金银花精油的主体呈香成分为单萜和倍半萜类化合物,占金银花精油含量的75.30％,其中,金银花精油中芳樟醇及其衍生物含量大于25.60％;最佳金银花精油-β-环糊精包合物制备工艺条件为金银花精油与β-环糊精的包合比例1∶10(mL∶g)、包合温度60℃、搅拌时间3h、烘干温度45℃,在此最优条件下,金银花精油的包合率为68.95％.[结论]水蒸气蒸馏法和饱和水溶液法可分别用于金银花精油及其与β-环糊精包合物的制备.
Abstract
[Objective] To optimize the preparation processes for honeysuckle essential oil and its inclusion compound with β-cyclodextrin.[Method] Honeysuckle essential oil was prepared with steam distillation method,the composition and content of principal aroma components of the honeysuckle essential oil were analyzed with GC-MS.Honeysuckle essential oil-β-cyclodextrin inclusion compound was prepared with saturated water solution method,and the inclusion rate of honeysuckle essential oil was used as evaluation index to investigate the influences of the proportion of honeysuckle essential oil and β-cyclodextrin,the inclusion temperature,the stirring time and the drying temperature on the preparation process of the inclusion compound with orthogonal test.[Result] The yield of honeysuckle essential oil prepared by steam distillation method was 0.12％,after analysis with GC-MS,the principal aroma components of the honeysuckle essential oil were monoterpenoids and sesquiterpenoids,and the total content of these two kinds of compounds was 75.30％.Among them,the content of linalool and its derivatives in honeysuckle essential oil was more than 25.60％.The optimum preparation process conditions for honeysuckle essential oil-β-cyclodextrin inclusion compound were as follows:the proportion of honeysuckle essential oil and β-cyclodextrin was 1∶10 (mL∶ g),the inclusion temperature was 60 ℃,the stirring time was 3 h and the drying temperature was 45 ℃.Under the optimum conditions,the inclusion rate of honeysuckle essential oil was 68.95％.[Conclusion] The steam distillation method and the saturated water solution method can be respectively used for the preparation of honeysuckle essential oil and its inclusion compound with β-cyclodextrin.
关键词
金银花精油/水蒸气蒸馏法/β-环糊精/包合物/正交试验Key words
Honeysuckle essential oil/Steam distillation method/β-cyclodextrin/Inclusion compound/Orthogonal test引用本文复制引用
基金项目
大学生创新创业训练计划项目(201510452026)
山东省重点研发计划项目(2015GNC110036)
出版年
2017
国家科技期刊平台
NSTL
维普
万方数据