一种蛹虫草固体饮料对小鼠肠道菌群的影响
Effect of a Kind of Cordyceps militaris Solid Beverage on the Intestinal Flora of Mice
贾俊杰 1颜迟 1邵颖 1陈安徽 1刘辉1
作者信息
- 1. 江苏省食品资源开发与质量安全重点建设实验室,徐州工程学院,江苏徐州221008
- 折叠
摘要
[目的]研究蛹虫草速溶粉(佑元茶)对小鼠肠道菌群的影响.[方法]利用抗生素(青霉素钠)构建肠道菌群失调小鼠模型,以正常小鼠为对照,采用菌落计数法考察一种蛹虫草固体饮料对肠道菌群失调小鼠的肠道修复作用.[结果]蛹虫草固体饮料的高、中剂量组小鼠的体重显著高于其他组(P<0.05).高、中、低3个剂量组小鼠肠道中的益生菌乳酸杆菌和双歧杆菌数量均显著高于模型组,且条件致病菌肠球菌数量均显著少于模型组(P<0.05);3个剂量组中,中、高剂量组与低剂量组间亦存在显著性差异(P<0.05),但中高剂量组间差异不明显.[结论]蛹虫草固体饮料对于抗生素干扰引起的肠道菌群失调具有较好的修复作用,可调节并保持肠道微生态菌群的平衡.
Abstract
[Objective] The research aimed to study the the effect of a kind of Cordyceps militaris instant powder ( Youyuan tea) on the intes-tinal flora of mice.[ Method] Antibiotics( penicillin sodium) was used to build the alteration of intestinal flora illness model of mice , the nor-mal mice were used as control and the colony counting method was used to explore the effect of a kind of Cordyceps militaris solid beverage on the intestinal flora of mice.[Result]The weight of mice in high and medium dose group was higher than other groups dramatically(P<0.05). The quantity of probiotics such as lactobacillus and bifidobacterium in the mice intestinal canal of dose groups was higher than that of model group, and the quantity of conditioned pathogen such as enterococcus was lower than the model group(P <0.05);there was a significant difference existed among the low dose group and the middle,high dose group,but the difference between middle and high dose groups was not obvious.[ Conclusion] The Cordyceps militaris solid beverage has better recovery effect on the alteration of intestinal flora which was caused by antibiotics, and it also could adjust and maintain the balance of intestinal microecology .
关键词
蛹虫草/固体饮料/抗生素/肠道菌群Key words
Cordyceps militaries/Solid beverage/Antibiotics/Intestinal flora引用本文复制引用
基金项目
江苏省科技计划项目(BN2016003)
江苏省科技计划项目(BE2017352)
江苏省科技计划项目(BN2015012)
江苏省高校自然科学研究重大专项(15KJA180008)
出版年
2017
国家科技期刊平台
NSTL
维普
万方数据