Ultrasonic assisted extraction method was used to extract polysaccharide from Zingiber officinale Roscoe. First, single factor and or-thogonal test were used to optimize the extraction process of Zingiber officinale Roscoe polysaccharide. The experimental results showed that the optimal extraction process of Zingiber officinale Roscoe polysaccharide was as follows: liquid to material ratio 1 : 20, homogenization time 5 min, homogenization temperature 70 ℃, ultrasonic time 80 min and ultrasonic temperature 80 ℃. Under the condition of ultrasonic power of 100 W, the yield of polysaccharide was 12.56％. Then, the antioxidant activity of the extracted Zingiber officinale Roscoe polysaccharide was determined. The experimental results showed that the hydroxyl radical scavenging ability of Zingiber officinale Roscoe polysaccharide reached 90.96％ at 5 mg/mL, and the reducing power was the strongest.
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