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不同生长年限甘草不同药用部位质量研究

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[目的]探究新疆巴音郭楞蒙古自治州库尔勒市不同药用部位和生长年限的甘草中甘草苷和甘草酸含量差异,为有效控制其质量提供依据.[方法]以《中国药典》(2020年版)规定的甘草中有效成分甘草苷和甘草酸为检测标准,采用高效液相色谱法测定并比较新疆巴音郭楞蒙古自治州库尔勒市甘草药材不同药用部位和生长年限中甘草苷和甘草酸含量,以化学成分角度来探讨中药的质量.[结果]甘草各药用部位甘草苷和甘草酸含量从高到低依次为侧根>主根>全根>浮根>须根>芦头;侧根、主根和全根中甘草苷含量符合《中国药典》(2020年版)的规定(≥0.50%);侧根中甘草酸含量符合《中国药典》(2020 年版)的规定(≥2.0%);3 年生甘草药材质量最佳.[结论]传统加工方式中直接除去的须根,可作为提取甘草苷的原材料.该研究可为甘草的采收、加工、规格等级划分提供参考依据.
Study on the Quality of Different Medicinal Parts of Glycyrrhiza uralensis with Different Growth Years
[Objective]To explore the contents of liquiritin and glycyrrhizic acid in different medicinal parts and growth years of Glycyrrhiza uralensis in Korla,Bayingol Mongolia Autonomous Prefecture,Xinjiang,so as to provide basis for effective quality control.[Method]Taking the active components liquiritin and glycyrrhizic acid in Glycyrrhiza uralensis stipulated in the 2020 edition of Pharmacopoeia of the People's Republic of China as the detection standard,the contents of liquiritin and glycyrrhizic acid in different medicinal parts and growth years of Gly-cyrrhiza uralensis in Korla,Bayingol Mongolia Autonomous Prefecture of Xinjiang were determined and compared by HPLC,and the quality of traditional Chinese medicine was discussed from the point of view of chemical composition.[Result]The order of the content of liquiritin and glycyrrhizic acid in various medicinal parts of licorice was lateral root>main root>whole root>floating root>fibrous root>reed head;the contents of liquiritin in lateral root,main root and whole root met the requirements of the Chinese Pharmacopoeia(2020 edition)(≥0.50% );the con-tent of glycyrrhizic acid in lateral roots met the requirements of the Chinese Pharmacopoeia(2020 edition)(≥2.0% );three-year-old Glycyr-rhiza uralensis had the best quality.[Conclusion]The fibrous root directly removed in the traditional processing method can be used as the raw material for the extraction of liquiritin.This study can provide reference for the harvesting,processing and grading of licorice.

Glycyrrhiza uralensisQuality studyMedicinal partsGrowth yearsLiquiritinGlycyrrhizic acid

王永福、范伟兵、马恩耀、吴进轩、李红平、安子龙、陈建雷、朱宣青、王文博

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甘肃广药白云山中药科技有限公司,甘肃 定西 743000

广东汉潮中药科技有限公司,广东 广州 510000

甘草 质量研究 药用部位 生长年限 甘草苷 甘草酸

2025

安徽农业科学
安徽省农业科学院

安徽农业科学

影响因子:0.413
ISSN:0517-6611
年,卷(期):2025.53(2)