Objective To explore the risk factors of gastric cancer patients in key areas of the Huaihe River Basin,and to provide a basis for the primary prevention and control of gastric cancer in the Huaihe River Basin.Methods New cases of gastric cancer with a tumor diagnosis ICD-10 code of C16 between January 1,2020 and July 31,2021 were selected from the local regional(county)cancer registry system as the case group.In the same region,same gender,no previous history of ma-lignancy,and age±5 years were selected as the control group according to the 1∶2 matching principle.Questionnaires and body measurements were administered to both groups.A total of 240 gastric cancer cases and 480 control cases were includ-ed.Risk factors of gastric cancer were analyzed by logistic regression using SAS.Results The results of multivariate logis-tic regression analysis showed that salty taste in diet(OR=2.161,95％CI:1.141-4.095),preference for spicy food(OR=1.773,95％CI:1.057-2.975),exposure to second-hand smoke(OR=1.963,95％CI:1.168-3.299),frequent anger(OR=8.704,95％CI:3.582-21.147)and history of digestive disorders(OR=2.302,95％CI:1.329-3.988)were risk factors for the development of gastric cancer.However,BMI(OR=0.697,95％CI:0.639-0.761),high literacy(OR=0.454,95％CI:0.248-0.830)and daily water intake ≥ 1 500 mL(OR=0.443,95％CI:0.217-0.906)were negatively associated with the occurrence of gastric cancer.Conclusion The development of gastric cancer is associated with dietary habits,second-hand smoke exposure,personality and emotional characteristics,and history of digestive system diseases.Awareness of cancer pre-vention and control among the population,health education and behavioral guidance should be further strengthened to control cancer risk factors and reduce the risk of gastric cancer.
维普
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