Analysis of key epidemiological indicators and clinical features of different variants of SARS-CoV-2
Objective To analyze the epidemiological indicators and clinical manifestations of coronavirus disease 2019(COVID-19)with different variants,and to provide a reference for the prevention and control of SARS-CoV-2.Methods The data on social demographic characteristics,epidemiological characteristics,clinical manifestations,and laboratory tests of COVID-19 cases in Anhui Province from 2020 to 2022 were collected.SPSS 21.0 was used to analyze the epidemiological and clinical characteristics of patients infected with different variants.Results A total of 2 416 cases of COVID-19 were in-cluded,including 990 cases of original strain infection,22 cases of B.1.1.317 evolutionary branch infection,12 cases of Delta infection,and 1 392 cases of Omicron infection.The differences in case classification,clinical type,and Ct value a-mong different variants of SARS-CoV-2 were statistically significant(P＜0.001),and fever was the main clinical feature of the first symptoms of infection among different variants.Moreover,the incubation periods of different strains were 9.0(5.0,11.0)days for the original strain,8.0(4.0,12.0)days for B.1.1.317,3.5(3.0,9.0)days for Delta,and 3.0(1.8,5.6)days for Omicron,and the differences were statistically significant(H=42.448,P＜0.001).The median generational inter-val was 6.0 days in the original strain and 3.0 days in the Omicron variant.Conclusion The Omicron variant of SARS-CoV-2 is more infectious than other strains,and is more likely to result in hidden transmission.
NETL
NSTL
万方数据
