Analysis of drug resistance and molecular typing of 128 Salmonella enteritis strains in Anhui Province from 2018 to 2021
Objective To understand the drug resistance spectrum and molecular typing characteristics of Salmonella enteri-tis in Anhui Province.Methods 128 strains of Salmonella enteritidis isolated and cultured in 6 cities of Anhui Province from 2018 to 2021 were tested for drug sensitivity.The molecular typing was performed by pulsed field gel electrophoresis(PFGE),and the cluster analysis of PFGE patterns was performed by BioNumerics 6.6 software.Results The 128 strains of Salmonella enterica were resistant to 14 antibiotics to varying degrees,and the highest resistance rate was nalidixic acid(98.43％,126/128),followed by ampicillin(87.50％,112/128),and ampicillin/sulbactam(69.53％,89/128).The ge-nomes of the 128 strains of Salmonella enterica were sectioned into 35 banding types,and the similarity among the various banding types ranged from 67.10％to 100.00％.Conclusion The drug resistance rate of Salmonella enteritidis was high in six cities in Anhui Province,and the similarity of PFGE banding was high,so the investigation of infectious sources should be strengthened and the use of antibiotics should be standardized.
SalmonellaeDrug resistancePulsed-field gel electrophoresisMolecular typing
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