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厦门市2021年489名居民乙型肝炎病毒感染状况及影响因素分析

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目的 探索厦门市人群乙型肝炎病毒(HBV)感染状况及其影响因素,为制定预防控制措施提供参考.方法 采用多阶段分层抽样方法,2021年在厦门市2个区6个居委会(村)抽取15个年龄组489名调查对象,对其开展问卷调查并采血检测HBV感染5项指标,计算HBV感染率等指标,采用logistic回归分析HBV感染的影响因素.结果 共调查489人,性别分布以女性为主,265人,占54.19%;年龄以0~5岁为主,190人,占38.85%;婚姻状况以未婚为主,365人,占74.64%;职业以学生为主,147人,占30.06%;接种乙肝疫苗以≥3剂次为主,388人,占79.35%.489名调查对象中,115名为HBV感染者,HBV感染率为23.52%,标化率为40.37%.logistic回归分析结果显示,农民(OR=7.301,95%CI:1.018~52.342)、6~10 岁(OR=10.859,95%CI:1.012~116.578)、11~20 岁(OR=9.583,95%CI:1.138~80.682)、21~50 岁(OR=7.214,95%CI:1.016~51.213)和≥ 51 岁(OR=11.752,95%CI:2.342~58.973)是 HBV 感染的危险因素;接种乙肝疫苗 ≥3 剂次(OR=0.137,95%CI:0.021~0.892)是HBV感染的保护因素.结论 厦门市乙型肝炎防控工作取得了一定成效,但仍有提升的空间.
Analysis of hepatitis B virus infection status and influencing factors among 489 residents in Xiamen City in 2021
Objective To explore hepatitis B virus(HBV)infection status and its influencing factors among people in Xia-men City,and provide guidance for the formulation of prevention and control measures.Methods A multi-stage stratified sampling method was applied to select 489 participants in 15 age groups from 6 neighborhood committees(villages)in 2 districts of Xiamen City in 2021.A questionnaire survey was conducted and blood samples were collected to test for 5 indi-cators of HBV infection.The HBV infection rate and other indicators were calculated,and logistic regression analysis was used to identify the influencing factors of HBV infection.Results A total of 489 participants were investigated,and 265 of them were female,accounting for 54.19%;age range was mainly 0-5,with 190 participants,accounting for 38.85%;the ma-rital status was mainly unmarried,with 365 participants,accounting for 74.64%;the main occupation was students,with 147 participants,accounting for 30.06%;388 participants(79.35%)received≥3 doses of hepatitis B vaccine.Among 489 survey subjects,115 were HBV infected,with an HBV infection rate of 23.52%and a standardized rate of 40.37%.The lo-gistic regression analysis results showed that farmers(OR=7.301,95%CI:1.018-52.342),6-10 years old(OR=10.859,95%CI:1.012-116.578),11-20 years old(OR=9.583,95%CI:1.138-80.682),21-50 years old(OR=7.214,95%CI:1.016-51.213),and≥51 years old(OR=11.752,95%CI:2.342-58.973)were risk factors for HBV infection;≥ 3 do-ses hepatitis B vaccine(OR=0.137,95%CI:0.021-0.892)was the protective factor of HBV infection.Conclusions The hepatitis B prevention and control efforts in Xiamen City have shown certain effectiveness,but there is still room for im-provement.

PopulationHepatitis B virus infectionInfluencing factors

谢群、张怡盾、马姗姗、张建梅、刘红莲、林杨琛、张金华

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厦门市疾病预防控制中心免疫规划处,福建厦门 361021

人群 HBV感染 影响因素

2024

安徽预防医学杂志
安徽省预防医学会 安徽省疾病预防控制中心

安徽预防医学杂志

影响因子:0.43
ISSN:1007-1040
年,卷(期):2024.30(6)