摘要
近几年SARS-CoV-2以其极高的突变率和传染性在全球流行,COVID-19大流行成为引起国际关注的突发公共卫生事件.本文对SARS-CoV-2病原学特征、体液免疫应答特征、自然感染和疫苗接种后体液免疫应答和抗体检测技术的应用进行综述,为疫苗研发和公共卫生政策的制定提供科学依据.
Abstract
In recent years,SARS-CoV-2 has become a public health emergency of international concern due to its high muta-tion rate,and the COVID-19 pandemic has become a public health emergency of international concern.In this paper,we re-view the pathogenetic characteristics of SARS-CoV-2,the characteristics of humoral immune response to SARS-CoV-2,the humoral immune response to SARS-CoV-2 after natural infection and vaccination,and the application of SARS-CoV-2 anti-body detection technology,in order to provide scientific basis for vaccine research and development,and the formulation of public health policies.