安徽医学2014,Issue(4) :420-421,422.DOI:10.3969/j.issn.1000-0399.2014.04.004

脑型Wilson病患者智力水平及智力结构的研究

Study on intelligence level and intelligence structure in brain type patients with Wilson's disease

李波 王共强 韩咏竹 韩永升 马心峰
安徽医学2014,Issue(4) :420-421,422.DOI:10.3969/j.issn.1000-0399.2014.04.004

脑型Wilson病患者智力水平及智力结构的研究

Study on intelligence level and intelligence structure in brain type patients with Wilson's disease

李波 1王共强 1韩咏竹 1韩永升 1马心峰1
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作者信息

  • 1. 230061 合肥 安徽中医药大学神经病学研究所附属医院
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摘要

目的:通过神经心理学测验评估脑型Wilson病(Wilson's disease,WD)患者晶体智力和流体智力水平,探讨其智力结构变化的特点及相关因素。方法选取32例脑型WD患者为研究对象,采用韦氏智力量表、瑞文标准推理测验( R′SPM )进行晶体智力和流体智力测评,运用SPSS 11.5软件分析患者的晶体智力、流体智力变化及相关因素。结果43.75%脑型WD患者晶体智力水平下降,78.13%脑型WD患者流体智力水平下降,瑞文标准推理测验智商(RWIQ)得分低于韦氏智力测定全量表智商(FIQ)得分(P<0.05);韦氏智力测定言语量表智商(VIQ)、韦氏智力测定操作量表智商(PIQ)与FIQ呈正相关(P<0.05),瑞文标准推理测验E分测验(RWE)、性别与RWIQ呈正相关(P<0.05),FIQ与RWIQ无相关性(P>0.05)。结论脑型WD患者的智力结构存在不均衡受损,流体智力水平下降较晶体智力水平更为明显。流体智力和晶体智力不可相互替代。

Abstract

Objective Through conducting neuropsychological test to evaluate crystallized intelligence and fluid intelligence of brain type patients with Wilson's disease ( WD) ,to analyze the characteristics of intelligence structure changing and other related factors .Methods Wechsler intelligence test and Raven's standard progressive matrices ( R'SPM) were conducted among 32 brain type WD patients ,in order to assess crystallized intelligence and fluid intelligence .The diversities of patients crystallized intelligence , fluid intelligence and other related factors were analysed by using SPSS 11.5 software.Results 43.75%brain type WD patients showed a decrease in crystallized intelligence while 78.13%patients showed fluid intelligence drop .Moreover,Raven's standard progressive matrices intelligence quotient (RWIQ) ranking was significantly less than full measuring scale intelligence quotient (FIQ) (P<0.05),verbal intelligence quotient (VIQ) and performance intelligence quotient (PIQ )appeared significantly positive correlation (P<0.05) with FIQ.In addition,RWE,gender showed significantly positive correlation(P<0.05) with RWIQ;however,FIQ did not show any relation with RWIQ(P>0.05).Conclusion Brain type WD pa-tients'intelligence structure has unbalanced damage ,and fluid intelligence decreases more obviously than crystallized intelligence .The fluid in-telligence and crystallized intelligence cannot replace with each other .

关键词

Wilson病/肝豆状核变性/晶体智力/流体智力/相关因素

Key words

Wilson's disease/Hepatolenticular degeneration/Crystallized intelligence/Fluid intelligence/Related factors

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基金项目

安徽省卫生厅科研基金(2012zy65)

出版年

2014
安徽医学
安徽省医学情报研究所

安徽医学

CSTPCD
影响因子:1.123
ISSN:1000-0399
被引量6
参考文献量5
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