Study on the factors affecting ICU acquired weakness in patients receiving first early enteral nutrition
Objective To explore the factors affecting intensive care unit acquired weakness(ICU-AW)in patients receiving first early enteral nutrition.Method A retrospective study was conducted on 212 patients who received first early enteral nutrition in the Emer-gency Intensive Care Unit(EICU)of our hospital from January 2021 to December 2022.The patients were divided into the ICU-AW group and non ICU-AW group based on whether ICU-AW occurred during enteral nutrition treatment.General information,early enteral nutrition initia-tion time,caloric-protein supply and intra-abdominal pressure values on day 7 of enteral nutrition treatment were recorded for the two groups of patients,then the relationship between intra-abdominal pressure and ICU-AW was analyzed and the factors affecting ICU acquired weak-ness were explored.Results There were statistical differences between the two groups in age,mechanical ventilation,acute physiological and chronic health(APACHE Ⅱ)scores,blood sugar,renal replacement therapy,corticosteroid use,average daily calorie intake,average daily pro-tein intake,intestinal nutrition intoleranceand abdominal pressure on day 7 of enteral nutrition treatment(P<0.05).The intra-abdominal pres-sure in the ICU-AW group was higher than that in the non ICU-AW group[(16.42±1.52)cmH2O vs(12.88±2.19)cmH2O],with a statisti-cally significant difference(P<0.05).Logistic regression analysis showed that the risk factors for ICU-AW were age,high APACHE Ⅱ score,mechanical ventilation,use of corticosteroids,low average daily calorie and protein intake,intestinal nutrition intoleranceand high abdominal pressure after seven days of enteral nutrition treatment.Conclusion Elderly age,high APACHE Ⅱ score,mechanical ventilation,use of corti-costeroids,low average daily calorie and protein levels,low average daily calorie and protein levels,intestinal nutrition intoleranceand high ab-dominal pressure after seven days of enteral nutrition treatment are risk factors for ICU-AW in patients undergoing initial enteral nutrition treatment.Attention should be paid and targeted early intervention should be given.
Critically ill patientsEnteral nutritionIntensive care unit acquired weaknessIntra abdominal pressure
NETL
NSTL
万方数据
维普
