摘要
目的 分析63例儿童腐蚀性食管炎的内镜特征及危险因素.方法 回顾性分析2018年3月至2023年10月郑州大学附属儿童医院消化内科收治的63例腐蚀性食管炎的患者资料,根据内镜诊断分级分为0～1级组(n=16)和2～3级组(n=47),采用单因素分析及多因素logistic回归分析其影响因素.结果 63例患者中,最常见的症状是口唇红肿糜烂,占52.38％(33/63);食管炎损伤程度处于0级4例,1级12例,2a级27例,2b级18例,3级2例.单因素分析结果显示,两组在年龄、居住地、误服腐蚀性物质性质、误服量及误服腐蚀性物质浓度方面比较,差异具有统计学意义(P<0.05).Logistic回归分析结果显示,年龄≤3岁(OR=1.635,P=0.029)、居住地为城市(OR=2.302,P=0.001)、误服碱性腐蚀性物质(OR=7.265,P=0.001)、误服量>5 mL(OR=3.274,P=0.035)、误服高浓度腐蚀性物质(OR=4.552,P=0.017)是儿童腐蚀性食管炎内镜分级的危险因素.结论 儿童腐蚀性食管炎以食管浅表溃疡形成为主要表现;年龄≤3岁、居住地为城市、误服碱性腐蚀性物质、误服量>5 mL以及误服高浓度腐蚀性物质是儿童腐蚀性食管炎的危险因素.
Abstract
Objective To analyze the endoscopic characteristics and risk factors of 63 children with corrosive esophagitis. Methods A retrospective analysis was conducted on the clinical data of 63 children with corrosive esophagitis treated in our hospitalfrom March 2018 to October 2023,according to the grading of endoscopic diagnosis,the patients were divided into 0～1 level group (n=16) and 2～3 level group (n=47),and the influencing factors were analyzed using univariate analysis and multivariate logistic regression analysis. Results Among 63 pa-tients,the most common symptom was redness,swelling,and erosion of the lips,accounting for 52.38％ (33/63),endoscopic examination showed that the degree of esophagitis injury was at grade 0 in 4,grade 1 in 12,grade 2a in 27,grade 2b in 18,and grade 3 in 2. The results of univariate analysis showed that there were statistically obvious differences in age,place of residence,nature of corrosive substances ingested by mistake,dosage of corrosive substances ingested by mistake,and concentration of corrosive substances ingested by mistake between the two groups(P＜0.05).The results of logistic regression analysis showed that age ≤ 3 years old (OR=1.635,P=0.029),residence in a city (OR=2.302,P=0.001),ingestion of alkaline corrosive substances (OR=7.265,P=0.001),ingestion of＞5mL (OR=3.274,P=0.035),and ingestion of high con-centration corrosive substances (OR=4.552,P=0.017) were risk factors for endoscopic grading of children with corrosive esophagitis. Conclu-sions Corrosive esophagitis in children often manifests as superficial esophageal ulcers.Age ≤ 3 years old,residence in a city,ingestion of al-kaline corrosive substances by mistake,ingestion of＞5 mL,and ingestion of high concentrations of corrosive substances by mistake are risk factors for children with corrosive esophagitis.
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