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慢性便秘患者合并焦虑 抑郁状态的影响因素分析

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目的 探究慢性便秘(CC)患者合并焦虑、抑郁状态的影响因素.方法 对2021年4月至2023年7月安徽医科大学附属六安医院消化内科收治的150例符合CC诊断标准的患者采用病史采集、问卷调查的方式进行数据统计,根据焦虑、抑郁评分分为焦虑组、无焦虑组和抑郁组、无抑郁组,比较各组一般资料(性别、年龄、身体质量指数、便秘病程、有无腹痛、便秘治疗情况、学历)、便秘患者症状自评表(PAC-SYM)评分、便秘患者生存质量自评量表(PAC-QOL)评分、Kolcaba的舒适状况量表(GCQ)评分、饮食态度测试(EAT-26)评分,并对于CC患者产生焦虑、抑郁状态的危险因素行单因素和多因素logistic回归分析.结果 CC患者中,合并焦虑48例(32.0%),合并抑郁41例(27.3%),进食障碍(ED)高危人群46例(30.7%).合并焦虑、抑郁的CC患者PAC-SYM评分、PAC-QOL评分高于无焦虑、抑郁组,GCQ评分低于无焦虑、抑郁组,ED高危人群占比高于无焦虑、抑郁组,差异均具有统计学意义(P<0.05).病程≥3年、有腹痛为CC患者合并焦虑、抑郁的独立危险因素,曾行便秘治疗是其合并焦虑的保护因素.结论 CC患者合并焦虑、抑郁会加重便秘症状,降低生活质量与舒适程度,病程≥3年及有腹痛症状是其合并焦虑、抑郁状态的独立危险因素,曾行便秘治疗是其合并焦虑的保护因素.
Factors influencing anxiety and depression in patients with chronic constipation
Objective To explore the influencing factors of anxiety and depression in patients with chronic constipation (CC). Meth-ods From April 2021 to July 2023,data were collected from 150 patients diagnosed with CC in the Department of Gastroenterology at the Af-filiated Hospital of Anhui Medical University. Patients were divided into the anxiety group and non-anxiety group,the depression group and non-depression group based on anxiety and depression scores. General information (gender,age,BMI,duration of constipation,presence of ab-dominal pain,constipation treatment,education level),PAC-SYM score,PAC-QOL score,GCQ score,and EAT-26 score were compared be-tween the two groups. Univariate and multivariate logistic regression analyses were used to determine the risk factors for anxiety and depression in CC patients. Results Among CC patients,48 (32.0%) had anxiety,41 (27.3%) had depression,and 46 (30.7%) were in the high-risk group for eating disorders. CC patients with anxiety and depression had significantly higher PAC-SYM and PAC-QOL scores compared to those with-out anxiety and depression,while the GCQ score was significantly lower in the anxiety and depression groups. The proportion of patients in the high-risk group for eating disorders was significantly higher than that in the non-anxiety and depression groups,with statistically significant differences. Disease duration ≥3 years and presence of abdominal pain were independent risk factors for anxiety and depression in CC patients,while receiving constipation treatment was a protective factor for anxiety. Conclusion Anxiety and depression in CC patients worsen constipa-tion symptoms and reduce quality of life and comfort. Disease duration ≥3 years and presence of abdominal pain are independent risk factors for anxiety and depression,while receiving constipation treatment is a protective factor for anxiety.

Chronic constipationAnxiety and depression statusSymptomsQuality of lifeEating disorders

李晨、魏文俊、刘黎、汤海涛

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233030 安徽蚌埠 蚌埠医科大学研究生院

237000 安徽六安 安徽医科大学附属六安医院消化内科

慢性便秘 焦虑、抑郁状态 症状 生活质量 进食障碍

安徽省六安市人民医院院级课题

2020kykt22

2024

安徽医学
安徽省医学情报研究所

安徽医学

CSTPCD
影响因子:1.123
ISSN:1000-0399
年,卷(期):2024.45(9)