Factors influencing anxiety and depression in patients with chronic constipation
Objective To explore the influencing factors of anxiety and depression in patients with chronic constipation (CC). Meth-ods From April 2021 to July 2023,data were collected from 150 patients diagnosed with CC in the Department of Gastroenterology at the Af-filiated Hospital of Anhui Medical University. Patients were divided into the anxiety group and non-anxiety group,the depression group and non-depression group based on anxiety and depression scores. General information (gender,age,BMI,duration of constipation,presence of ab-dominal pain,constipation treatment,education level),PAC-SYM score,PAC-QOL score,GCQ score,and EAT-26 score were compared be-tween the two groups. Univariate and multivariate logistic regression analyses were used to determine the risk factors for anxiety and depression in CC patients. Results Among CC patients,48 (32.0%) had anxiety,41 (27.3%) had depression,and 46 (30.7%) were in the high-risk group for eating disorders. CC patients with anxiety and depression had significantly higher PAC-SYM and PAC-QOL scores compared to those with-out anxiety and depression,while the GCQ score was significantly lower in the anxiety and depression groups. The proportion of patients in the high-risk group for eating disorders was significantly higher than that in the non-anxiety and depression groups,with statistically significant differences. Disease duration ≥3 years and presence of abdominal pain were independent risk factors for anxiety and depression in CC patients,while receiving constipation treatment was a protective factor for anxiety. Conclusion Anxiety and depression in CC patients worsen constipa-tion symptoms and reduce quality of life and comfort. Disease duration ≥3 years and presence of abdominal pain are independent risk factors for anxiety and depression,while receiving constipation treatment is a protective factor for anxiety.
Chronic constipationAnxiety and depression statusSymptomsQuality of lifeEating disorders