Clinicopathologic analysis of 17 patients with dermatofibrosarcoma protuberans
Objective To explore the clinicopathologic characteristics ,diagnosis and differential diagnosis of dermatofibrosarcoma protu -berans (DFSP).Methods The clinical features,histopathological features,immunohistochemical features ,treatment and prognosis of 17 cases of DFSP were retrospectively analyzed .Results Among 17 cases of DFSP,13 cases were male and 4 cases were female with an average age of 37.3 years;there were 14 cases in the trunk,2 cases on head and 1 case in the forearm.DFSP lesions were located in the dermis and subcutaneous tissue ,and the tumor cells showed characteristic mat -like or car-like arrangement with invasive growth .Im-munohistochemistry showed that the expressions of CD 34 and Vimentin were diffusely positive,SMA focal areas of 2 cases were positive and S-100 was negative.Conclusions DFSP is a low grade malignant soft tissue tumor .It can be diagnosed by histology and immuno -histochemistry.Surgical resection is the main treatment method for DFSP .
DermatofibrosarcomaPathological conditions,Signs and symptomsDiagnosis,differential
NETL
NSTL
万方数据
维普
