Objective To investigate the correlation between cardiorespiratory fitness and visceral fat area in continuous ambulatory peritoneal dialysis(CAPD)patients.Methods A total of 52 patients who underwent regular CAPD in the Affiliated Hospital of Xu-zhou Medical University from May 2021 to October 2022 were included.Cardiorespiratory fitness(CRF)and visceral fat area(VFA)re-lated indicators were measured,with peak oxygen consumption(Peak VO2)as the gold standard for CRF,the patients were assigned into mild CRF impairment group(Peak VO2≥20 mL·kg-1·min-1)and moderate to severe CRF impairment group(Peak VO2<20 mL·kg-1·min-1).The differences in VFA and clinical indicators between the two groups were analyzed and independent risk factors for CRF were explored.Results The VFA,fat tissue index,edema index(ECW/TBW),fasting glucose,and triglycerides in the moderate to severe CRF impairment group were significantly higher than those in the mild CRF impairment group.The VFA in the moderate to severe CRF impairment group was 73.95(59.83,107.03)cm2,and the VFA in the mild CRF impairment group was 50.75(40.68,56.85)cm2.While the transferrin saturation in the moderate to severe CRF impairment group was significantly lower than that in the mild CRF im-pairment group(all P<0.05).Pearson or Spearman correlation analysis showed that Peak VO2 was negatively correlated with fat tissue index,visceral fat area,edema index,fasting glucose,CRP,diabetes status,and taking lipid-lowering drugs,respectively(all P<0.05),and positively correlated with transferrin saturation(r=0.32,P=0.021).There was no significant correlation between skeletal muscle in-dex and Peak VO2(P>0.05).The P<0.05 index in the single factor regression analysis was included in the multiple linear regression analysis,it was found that the visceral fat area(β=-0.40,P=0.002),urea clearance index(Kt/V)(β=0.31,P=0.013)and diabetes status(β=-0.38,P=0.026)were an independent risk factors for CRF.Conclusion Visceral fat area,urea clearance index and diabetes sta-tus are independent risk factors for low cardiorespiratory fitness in CAPD patients.Visceral fat area has a greater impact on cardiorespi-ratory fitness.Strengthening the management of visceral fat can reduce cardiovascular disease in CAPD patients.
维普
万方数据