Objective To analyze the characteristics of 4 cases of cerebral infarction with cheiro-oral syndrome as the only clinical manifestation,so as to improve understannding of the syndrome and avoid underdiagnosis and misdiagnosis.Methods The demograph-ic information,previous history,clinical manifestations,NIHSS score on admission,TOAST etiological classification,lesion sites shown in magnetic resonance imaging,head and neck angiography,treatment methods and long-term prognosis of 4 cerebral infarction pa-tients with cheiro-oral syndrome as the only clinical manifestation admitted to Fuyang People's Hospital from February 2021 to Novem-ber 2022 were retrospectively summarized.Results All the 4 patients had at least one risk factor for cerebral infarction,symptoms of ipsilateral perioral and hand numbness,lacunar cerebral infarction and mild stroke,with plaque or stenosis in the vascular wall of the head and neck,and were treated with anti-thrombolysis and lipid-controlling plaque fixation.Two cases had sequelae of sensory distur-bance in the long term prognosis,and 2 cases had no sequelae.Conclusions Cheiro-oral syndrome is most commonly seen in patients with cerebral infarction.There are similarities between this type of cerebral infarction and other types of cerebral infarction in terms of risk factors,TOAST classification,treatment and prognosis.However,limited cheiro-oral numbness is its unique clinical manifestation.
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