Clinical observation on the treatment of chronic spontaneous urticaria(spleen deficiency and damp heat syndrome)with Banxia Xiexin decoction and cetirizine hydrochloride tablets
Objective To observe the clinical efficacy of Banxia Xiexin decoction combined with cetirizine hydrochloride tablets in the treatment of chronic spontaneous urticaria(spleen deficiency and damp heat syndrome).Methods A total of 70 cases of chronic spontaneous urticaria(spleen deficiency damp heat syndrome)diagnosed in the dermatological clinic of Dazhou Integrated Hospital of Traditional Chinese and Western Medicine from January 2021 to June 2022 were randomly divided into treatment group and control group using a random number table,with 35 cases in each group.The control group was treated with cetirizine tablets,while the treat-ment group was treated with Banxia Xiexin decoction combined with cetirizine hydrochloride tablets.The total course of treatment was 6 weeks.At the beginning of the 4th and 6th week of treatment,the use of cetirizine hydrochloride tablets in the two groups was observed,and at the end of the 6th week of treatment,the clinical efficacy,total use of cetirizine tablets,urticaria activity score(UAS)and skin quality of life index(DQLI)scores,serum total immunoglobulin E(IgE)values,and adverse reactions of the two groups were observed.The recurrence was measured 8 weeks after treatment.Results A total of 60 cases were completed in this study,each group had 30 cas-es.At the beginning of the 4th and 6th week of treatment,the interval between the use of cetirizine hydrochloride tablets in the treat-ment group was clearly higher than that in the control group(the reduction rate of western medicine in the treatment group was higher than that in the control group)(P<0.05).After 6 weeks,the cure rate of the treatment group was 53.33%(16/30),while the cure rate of the control group was 20%(6/30),the recovery rate in the treatment group was higher than that in the control group(P<0.05);UAS and DQLI scores in the treatment group were lower than those in the control group(P<0.05);There was no obviously difference in adverse reactions between the two groups.Follow up 8 weeks after the treatment,the recurrence rate of treatment group was lower than that of control group(P<0.05).Conclusion The clinical effect of Banxia Xiexin decoction combined with cetirizine hydrochloride tablets in the treatment of chronic spontaneous urticaria(spleen deficiency damp heat syndrome)is definite,which can significantly shorten the course of disease and reduce the recurrence rate.
万方数据
维普
