Analysis of herbal prescriptions for treating patients with new coronavirus in a tertiary care chinese hospital
Objective To analyze the prescription information of The First Affiliated Hospital of Anhui University of Traditional Chi-nese Medicine for the treatment of Coronavirus Disease 2019(COVID-19)in December 2022 to provide reference for Chinese medicine treatment of COVID-19 and the review of prescriptions by Chinese pharmacists.Methods Information on prescriptions of traditional Chinese medicine used by outpatients with confirmed COVID-19 at Anhui Provincial Hospital of Traditional Chinese Medicine was col-lected,and Excel sheets were entered to organize prescription-related information data to establish a database of prescriptions of tradi-tional Chinese medicine for the treatment of COVID-19.The relevant information of TCM prescriptions for the treatment of COVID-19 was collected.The information of traditional Chinese medicine formulations used in the treatment of COVID-19 was explored,the asso-ciation pattern of drug compatibility in the formulations was excavated,and clustering methods were used to reveal drug use rules.Re-sults Among the prescriptions of 99 patients with COVID-19 treated with Chinese medicine,the age of the patients was mainly con-centrated above 60 years old,accounting for 40.40%;the frequency of prescriptions containing 11 to 15 kinds of medicinal materials in the treatment of COVID-19 with TCM was the highest,accounting for 48.49%;the dosage of Chinese medicine decoction prescriptions was mainly concentrated in the dosage of 10-15g,accounting for 66.67%.The days of TCM prescription were mostly within 3 days;the amount of Chinese medicine prescriptions spent less than 100 yuan accounted for 66%;according to the statistics of the frequency of use of TCM,the use of tonifying drugs was the most,accounting for 22%,followed by heat-clearing drugs 18.5%.In the analysis of TCM prescriptions for COVID-19,Glycyrrhiza glabra,Rhizoma Atractylodis Macrocephala,Bitter Almond,Poria,Chen Pi,Radix Bupleu-rum,Scutellaria were used more frequently.Among them,the combination of Scutellaria baicalensis with Glycyrrhiza glabra,Radix Bu-pleurum and Pinellia was particularly common in prescriptions.The compatibility of these herbs showed a high correlation,indicating that they were often used together in treatment.Conclusions There is a synergistic application pattern of Scutellaria baicalensis,Glyc-yrrhiza glabra,Radix Bupleurum and Pinellia in the treatment of COVID-19.Tonic,purgative,and detoxifying herbs are used most fre-quently in the treatment of COVID-19 herbal prescriptions,and the combination of related drugs and classical prescriptions provids a ba-sis and reference for the future diagnosis and treatment of novel coronavirus pneumonia.
New coronavirus pneumoniaTraditional Chinese medicinePrescription analysisDosing patternAssociation rule
万方数据
维普
